Myoinositol a new treatment option in Polycystic Ovarian Syndrome versus metformin-the conventional drug.
Not Applicable
- Conditions
- Health Condition 1: E282- Polycystic ovarian syndrome
- Registration Number
- CTRI/2019/09/021403
- Lead Sponsor
- Swati Jain
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
•All the females of age group 15-40 years fulfilling the Rotterdamâ??s criteria.3
•According to Rotterdamâ??s Criteria the affected must have :(atleast 2 out of 3)
(A) Oligovulation and /or anovulation .
(B)Hyperandrogenism(clinical/or biochemical) .
(C)Polycystic-ovaries,identified sonographically.
Exclusion Criteria
1.Patients already on other drug treatment for PCOS (like oral contraceptive pills)
2.Deranged kidney or liver function tests
3. Thyroid disorders
4.Known hypersensitivity to drugs
5. Galactorrhoea
6. Patient on any infertility treatment/fertility enhancing drugs
7. Established cases of diabetes mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢To compare the EFFECTIVENESS of Metformin versus Myoinositol in Polycystic ovarian syndrome patients in terms of weight reduction, Ferriman Gallwey score, menstrual cycle pattern after 3 months. After 6 months, complete radiological, biochemical and anthropometric reassessment will be done.Timepoint: Follow up will be done at 3rd and 6th month
- Secondary Outcome Measures
Name Time Method 1.To identify patients of PCOS patients by Rotterdamâ??s criteria. <br/ ><br>2.To study the role of Metformin in PCOS patients in terms of clinical improvement ,biochemical correction and radiological parameters . <br/ ><br>3.To study the role of Myoinositol in PCOS patients in terms of clinical improvement,biochemical correction and radiological parameters. <br/ ><br>4.Comparing Metformin versus Myoinositol in terms of clinical ,biochemical and radiological correction along with side effects. <br/ ><br>Timepoint: Follow up will be done at 3rd and 6th month