The effect of whey and casein protein ingestion prior to sleep on overnight muscle protein synthesis

Completed

• Conditions: spierherstel na inspanning; building muscle protein; muscle protein synthesis

• Registration Number: NL-OMON50719
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

- Males
- Aged between 18-35 years
- Healthy
- 18.5 <= BMI <= 30 kg/m2

Exclusion Criteria

- Smoking
- Sports/exercise > 4 sessions/week
- Lactose intolerant
- A history of neuromuscular problems
- Use of anticoagulation medication
- Recent (<1 y) participation in amino acid tracer [13C6 or 3,5-D2-tyrosine]
studies
- Individuals on any medications known to affect protein metabolism (i.e.
corticosteroids, non-steroidal anti-inflammatories, or prescription acne
medications)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Overnight myofibrillar protein synthesis rate</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Overnight mitochondrial protein synthesis rate<br /><br>- Plasma amino acid concentrations<br /><br>- Hunger VAS<br /><br>- Sleep VAS<br /><br>- Caloric intake at breakfast</p><br>