NCT05517512已完成不适用
Low Serum Pregnancy Protein 13 Early in Pregnancy Might Predict the Oncoming Gestational Hypertensive Disorders, Especially Early-onset Preeclampsia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- Serum biomarkers and GHD
研究概览
简要总结
the attendants of the clinic with a one-missed period (T0) underwent determination of baseline blood pressure (BP) measures and gave blood samples for estimation of levels of placental growth factor (PLGF), soluble fms-like tyrosine kinase-1 (sFlt-1) and pregnancy protein 13 (PP13). The same evaluation was repeated on the 6th, 24th, 32nd, and 36th gestational week (GW). Twenty non-pregnant women gave samples as a negative control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 33 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Normotensive women who attended the clinic with a one-missed period (T0)
排除标准
- •History of essential hypertension (HTN)
- •renal diseases
- •hepatic diseases
- •cardiac diseases
- •metabolic syndrome
- •body mass index (BMI) >35 kg/ m2
- •congenital heart diseases
结局指标
主要结局
Serum biomarkers and GHD
时间窗: 9 months
The primary outcome is the ability of early ELISA estimation of biomarkers for prediction of GHD
次要结局
未报告次要终点
研究者
Amr Sharaf Eldein
Assistant professor of gynecology
Benha University
研究点 (1)
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