NCT02547688撤回不适用
Assessment of the Tolerability of Dry Airflow in the Nasal Cavity During Sleep
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Subjective Tolerability using Questionnaire
研究概览
简要总结
Preliminary data show that high flow nasal air has been shown to reduce promote heat exchange due to evaporation of nasal mucus by the air flow resulting in heat loss. It is unclear whether unidirectional nasal airflow is well tolerated in healthy individuals. The central hypothesis of this proposal is that dry high flow nasal air will be sufficiently tolerated in healthy adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men and women
- •Able to consent
- •BMI<30kg/m2
排除标准
- •Previous diagnosis of obstructive sleep apnea or sleep disorder
- •History of Constant Positive Airway Pressure treatment for Obstructive Sleep Apnea
- •History of recurrent epistasis
- •Pregnancy (self-report)
- •Deviated nasal septum
- •Unstable cardiovascular disease (decompensated Congestive Heart Failure, myocardial infarction or revascularization procedures, unstable arrhythmias)
- •Uncontrolled hypertension with BP > 190/110
- •Daytime hypoxemia with oxygen saturation<90% (measured at history and physical examination)
- •Supplemental oxygen use
- •Work in transportation industry as a driver or pilot.
研究组 & 干预措施
Nasal High Flow
Other
All subjects are in this group
干预措施: Nasal High Flow (Device)
结局指标
主要结局
Subjective Tolerability using Questionnaire
时间窗: Baseline
Participant response to nasal high flow using 7 point Likert scale
次要结局
未报告次要终点
研究者
研究点 (2)
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