Clinical/preventive effect-confirmation study of liquid dentifrice containing 3 kinds of bactericides for periodontal disease
- Conditions
- Healthy male/female volunteers
- Registration Number
- JPRN-UMIN000048819
- Lead Sponsor
- KSO Corporation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Not provided
(1) At the screening test, volunteers who were determined as a patient having some dental caries (over C3 level) and/or severe periodontal disease. (2) Volunteers with medical treatment for diabetic, chronic kidney, digestive, lung or cancer diseases. (3) Volunteers having some kind of systemic disease, which has serious difficulty in participating this study. (4) Volunteers with toothbrushing not less than four times a day, including the brushing before and after breakfast, before their normal bedtime,etc. (5) Pregnant, possibly pregnant, or lactating women, during this clinical study. (6) Volunteers who are now under other clinical studies with some kind of medicine/food, or willing to participate in similar tests. (7) Volunteers having their stimulating saliva with no more than 3.0 mL for 5 min. (8) Volunteers having stimulating saliva with no more than a pH of 6.2. (9) Volunteers with some kind of allergy. (10) Volunteers equipped with removable denture, and/or dental implant on the dental object. (11) Volunteers straitening their teeth. (12) Volunteers falling into the habit of smoking. (13) Volunteers who have regularly used some kind of health food. (14) Volunteers who have took in some kind of antibiotic and/or antibacterial agent, regularly o r within the last month to the screening test. (15) Others who have been determined as ineligible for participation, judging from the principal /sub investigator's opinions.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method