Pancreatectomy for NET: External Evaluation of WHO 2017 Grading System

Completed

• Conditions: Pancreatic Surgery

• Registration Number: NCT03791346
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Aim: The aim of this study was to investigate the clinicopathological factors and to evaluate the prognostic accuracy of the new World Health Organization (WHO) 2017 grading system in pancreatic neuroendocrine tumor (PanNET) patients.

Methods: Data collected between 1997 and December 2017 were analyzed. Histological grading and staging was based on the WHO 2017 grading system. Outcome after surgery and predictors of overall survival (OS) and disease free survival (DFS) were evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 1997-01-01
• Primary Completion: 2017-12-01
• Status Verified: 2018-12
• Study First Submitted: 2018-12-31
• Study First Submitted QC: 2018-12-31
• Study First Posted: 2019-01-02
• Study Completion: 2019-02-01
• Last Update Submitted: 2019-04-17
• Last Update Posted: 2019-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Disease-free survival at 5 years	5 years	Disease-free survival (percentage of patients without recurrence) at 5 years. Disease-free survival (DFS) (time from diagnosis to time of first radiological evidence of local, regional, or distant relapse, or death due to any cause)

Secondary Outcome Measures

Name	Time	Method
Overall survival at 5 years	5 years	Overall survival (OS) (time from diagnosis until death, regardless of cause)

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France