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Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma

Not Applicable
Completed
Conditions
Ventilator Associated Pneumonia
Interventions
Registration Number
NCT01382446
Lead Sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Brief Summary

Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.

Detailed Description

To see a significant decrease in the bacterial load in the oral mucosa and subsequently, a decrease in the pathogenesis of Ventilator Associated Pneumonia through the use of an oral rinse containing 0.12% Chlorhexidine Gluconate as part of an oral care protocol. Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
66
Inclusion Criteria
  • Adults admitted to ICUs located in Tower Two Critical Care Units: Medical, Surgical, Medical #2, and Trauma Intensive Care Units.
  • Patients will be randomized to either treatment or standard group based on day of admission to Intensive Care Units. No limitation regarding gender, race, and ethnicity so that the sample will reflect "typical" Trauma population.
Exclusion Criteria
  • All patients admitted under "Doe" Status
  • All patients with acute cervical spine injuries or facial fractures that oral care will create further harm to the patient (physician order stating "no oral care to be given" will be in chart)
  • All patients with Oral Trauma or Oral Surgery
  • All minors (Study will be completed in Adult Critical Care Units)
  • Patients with allergy to chlorhexidine
  • Patients without Teeth, or with fewer than 6 teeth

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standard Oral Care RegimenToothpasteCurrent oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.
Chlorhexidine Oral Care RegimenChlorhexidine gluconateThis study will compare our current oral care practice with the use of Chlorhexidine Gluconate 0.12% (Peridex, 3M Corporation) Twice daily in addition to regularly scheduled oral care as a means to decrease the incidence of VAP utilizing evidence-based strategies.
Primary Outcome Measures
NameTimeMethod
Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients18 Months

Examination of number of participants who do not develop oral bacteria and Ventilator Associated Pneumonia when an oral rinse containing 0.12% Chlorhexidine Gluconate is used as part of a oral care protocol.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

St. Joseph's Hospital and Medical Center

🇺🇸

Phoenix, Arizona, United States

St. Joseph's Hospital and Medical Center
🇺🇸Phoenix, Arizona, United States
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