Evaluating Effectiveness of Chlorhexidine Gluconate Oral Care for Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients
研究概览
简要总结
Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.
详细描述
To see a significant decrease in the bacterial load in the oral mucosa and subsequently, a decrease in the pathogenesis of Ventilator Associated Pneumonia through the use of an oral rinse containing 0.12% Chlorhexidine Gluconate as part of an oral care protocol. Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults admitted to ICUs located in Tower Two Critical Care Units: Medical, Surgical, Medical #2, and Trauma Intensive Care Units.
- •Patients will be randomized to either treatment or standard group based on day of admission to Intensive Care Units. No limitation regarding gender, race, and ethnicity so that the sample will reflect "typical" Trauma population.
排除标准
- •All patients admitted under "Doe" Status
- •All patients with acute cervical spine injuries or facial fractures that oral care will create further harm to the patient (physician order stating "no oral care to be given" will be in chart)
- •All patients with Oral Trauma or Oral Surgery
- •All minors (Study will be completed in Adult Critical Care Units)
- •Patients with allergy to chlorhexidine
- •Patients without Teeth, or with fewer than 6 teeth
研究组 & 干预措施
Standard Oral Care Regimen
Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.
干预措施: Toothpaste (Other)
Chlorhexidine Oral Care Regimen
This study will compare our current oral care practice with the use of Chlorhexidine Gluconate 0.12% (Peridex, 3M Corporation) Twice daily in addition to regularly scheduled oral care as a means to decrease the incidence of VAP utilizing evidence-based strategies.
干预措施: Chlorhexidine gluconate (Drug)
结局指标
主要结局
Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients
时间窗: 18 Months
Examination of number of participants who do not develop oral bacteria and Ventilator Associated Pneumonia when an oral rinse containing 0.12% Chlorhexidine Gluconate is used as part of a oral care protocol.
次要结局
未报告次要终点
研究者
Madelon Petersen
Research Clinician
St. Joseph's Hospital and Medical Center, Phoenix