Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma
- Conditions
- Ventilator Associated Pneumonia
- Interventions
- Other: Toothpaste
- Registration Number
- NCT01382446
- Lead Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Brief Summary
Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.
- Detailed Description
To see a significant decrease in the bacterial load in the oral mucosa and subsequently, a decrease in the pathogenesis of Ventilator Associated Pneumonia through the use of an oral rinse containing 0.12% Chlorhexidine Gluconate as part of an oral care protocol. Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 66
- Adults admitted to ICUs located in Tower Two Critical Care Units: Medical, Surgical, Medical #2, and Trauma Intensive Care Units.
- Patients will be randomized to either treatment or standard group based on day of admission to Intensive Care Units. No limitation regarding gender, race, and ethnicity so that the sample will reflect "typical" Trauma population.
- All patients admitted under "Doe" Status
- All patients with acute cervical spine injuries or facial fractures that oral care will create further harm to the patient (physician order stating "no oral care to be given" will be in chart)
- All patients with Oral Trauma or Oral Surgery
- All minors (Study will be completed in Adult Critical Care Units)
- Patients with allergy to chlorhexidine
- Patients without Teeth, or with fewer than 6 teeth
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Standard Oral Care Regimen Toothpaste Current oral care protocol includes the use of 1.5% H2O2-coated swabs every four hours, toothbrushing with toothpaste every 12 hours, and use of continuous subglottic suction apparatus. Chlorhexidine Oral Care Regimen Chlorhexidine gluconate This study will compare our current oral care practice with the use of Chlorhexidine Gluconate 0.12% (Peridex, 3M Corporation) Twice daily in addition to regularly scheduled oral care as a means to decrease the incidence of VAP utilizing evidence-based strategies.
- Primary Outcome Measures
Name Time Method Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients 18 Months Examination of number of participants who do not develop oral bacteria and Ventilator Associated Pneumonia when an oral rinse containing 0.12% Chlorhexidine Gluconate is used as part of a oral care protocol.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
St. Joseph's Hospital and Medical Center
🇺🇸Phoenix, Arizona, United States
St. Joseph's Hospital and Medical Center🇺🇸Phoenix, Arizona, United States