Non-invasive Cardiac Output Monitoring in Patients With Burn Injuries
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Burns
- Sponsor
- Emory University
- Locations
- 1
- Primary Endpoint
- Rate of pressor use
- Status
- Withdrawn
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to describe the use of non-invasive cardiac output monitors (NICOM) in patients with burn injuries and to develop a protocol for NICOM in a burn unit.
Detailed Description
Appropriate fluid resuscitation in the first 24 hours after a burn injury directly influences patient outcome and morbidity. Currently, there is some controversy surrounding the over and under-resuscitation and endpoints of resuscitation using older fluid resuscitation formulas in patients with burn injury. The NICOM has been used in the resuscitation of patients with sepsis. The NICOM will be used in patients with burn injury to determine the patient's fluid responsiveness and the need for additional fluid boluses versus medications to increase the patient's blood pressure.
Investigators
Rachael Williams
Associate
Emory University
Eligibility Criteria
Inclusion Criteria
- •Burn greater than 20% TBSA (total body surface area)
Exclusion Criteria
- •Burn less than 20% TBSA (total body surface area)
Outcomes
Primary Outcomes
Rate of pressor use
Time Frame: Duration of hospital stay, an expected average of 30 days
Defined as number of subjects that required pressor support (administration of cardiovascular supportive agents)
Total volume of fluid given
Time Frame: 24 hours
The total volume of fluid given to the subjects in the first 24 hours
Secondary Outcomes
- Rate of pulmonary edema(Duration of hospital stay, an expected average of 30 days)
- Rate of acute renal failure(Duration of hospital stay, an expected average of 30 days)
- Length of stay in intensive care unit (ICU)(3 months)
- Length of hospital stay(3 months)