Prospective single arm open clinical trial to study the efficacy of Mutrakricchahar Ghanvati in mutrakrichha with special reference to urinary tract infection.
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- to evaluate the efficacy of mutrakricchar ghanvati in the managment of mutrakriccha
研究概览
简要总结
single arm open clinical trial
this study is conducting for evaluate efficacy of mutrakricchahar ghanvati in the management of mutrakriccha with special referance to urinary tract infection
after screening patients at OPD and IPD level 30 patients will be selected for trial, informed written consent will be taken in native langauge
Mutra refers to the urine and Krichrata refers to difficulty, hence disease Mutrakrichha include those forms of urinary disorders where Krichrata i.e. difficulty in the normal flow of urine is Dominant feature so all kinds of dysuria can be considered under this group. Urinary Tract Infection is one of the most common and potentially serious bacterial infection found Globally. It is common disorder accounting for 1-3% of consultations in general medical practice. According to Pub Med Central Article, Latest Prevalence rate of urinary tract infections are 10.1%. Where as, in Davidson’s principle and Practice for Medicine, it is about 37% .It is estimated that 40% women reported having UTI throughout their life. Typical features of UTI include frequency, urgency, dysuria, suprapubic pain during and after voiding, Urine appears cloudy, intense desire to pass more urine after micturition due to spasm of the inflammed bladder wall.
Null hypothesis-
Mutrakricchahar Ghanvati 500mg orally two tablets twice a day for 14 days is not effective in Mutrakriccha with special reference to UTI.
Alternate****hypothesis
Mutrakricchahar Ghanvati 500mg orally two tablets twice a day for 14 days is effective in Mutrakriccha with special reference to UTI.
Drug – Mutrakricchahar Ghanvati
◠Dose – 500 mg 2 tablets Twice a day
◠Anupana – Koshna Jala
◠Sevan Kala – Vyanodana (after food)
â— Duration - 14 days
â—Follow up - 7 th day , 14th day
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patient presenting with symptoms of Mutrakriccha with Urinary Tract Infection like Peeta Mutrata (Discolouration of urine), Bahurmutrata (Frequency of Urine), Sarakta Mutrata (Haematuria), Sadaha Mutrata (burning micturition), Saruja Mutrata (Painful Micturition), described in Ayurvedic classics 2 Without any bar of caste, sex, religion, occupation, socio-economic status.
- •3 Urine examination showing pus cells upto 30/hpf & RBC’s upto 15/hpf.
排除标准
- •1 Pregnant and lactating mothers.
- •2 Patients with serious illness like HJV, malignancy, Severe Cardiac disease, Uncontrolled stage at HTN.
- •3 Pt having Auto Immune disorders.
结局指标
主要结局
to evaluate the efficacy of mutrakricchar ghanvati in the managment of mutrakriccha
时间窗: 7th day, 14th day
次要结局
- 1 To evaluate the effect of Mutrakricchahar Ghanvati in Mutrakrichha(2 To Study the etiopathology of Mutrakrichha)
研究者
Dr Pradnya Govardhan Kashid
Seth Chandanmal Mutha Aryangla Vaidyak Mahavidyalaya , Satara