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Clinical Trials/NCT03223545
NCT03223545
Completed
Not Applicable

Stress Management to Support Women's Health

NYU Langone Health1 site in 1 country106 target enrollmentMay 7, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypertension
Sponsor
NYU Langone Health
Enrollment
106
Locations
1
Primary Endpoint
Blood pressure
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The purpose of this study is to evaluate a mindfulness-based cognitive therapy intervention delivered over the phone (MBCT-T) for women with prehypertension. MBCT-T is an evidence-based program that teaches meditation practices and cognitive strategies to reduce stress and negative emotions. It targets psychosocial risk factors that disproportionately affect women, including rumination (i.e., negative thinking) and low social support. Investigators plan to translate the established MBCT-T program into Spanish, conduct focus groups to inform cultural adaptations that may be needed for Latina women, and run a pilot randomized controlled trial to test the feasibility, acceptability and effects of MBCT-T on blood pressure and perceived stress in diverse women with prehypertension.

Detailed Description

Chronic stress is associated with the development of hypertension and cardiovascular disease. Reducing stress may be a useful prevention strategy for people at elevated risk of hypertension, including those with prehypertension. Women report different types of stress than men and may need tailored stress management programs.

Registry
clinicaltrials.gov
Start Date
May 7, 2018
End Date
July 17, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • English- or Spanish-speaking
  • A current patient of NYU/Bellevue Hospital Center (BHC) for the NYU study site or San Ysidro Health Center (SYHC) for the UCSD study site
  • BP measurement in prehypertensive range (SBP 120-139 mmHg or DBP 80-89 mmHg) recorded in EHR within past 6 months AND BP in prehypertensive range at screening
  • Willing to provide informed consent and comply with all aspects of the protocol
  • Willing to be audio-taped

Exclusion Criteria

  • Current use of antihypertensive medication
  • Clinically significant depressive symptoms (PHQ-8 ≥10)
  • Significant cognitive impairment, in the EHR or apparent during screening
  • History of current diagnosis of schizophrenia or other psychotic disorders
  • Current participation in another clinical trial

Outcomes

Primary Outcomes

Blood pressure

Time Frame: 3 Months

The mean of three BP readings taken by a trained RA with an automated and validated BP monitor (Microlife WatchBP Office) will be recorded at each visit. Participants will be seated comfortably for 5 minutes with feet flat on the ground prior to measurements. The device will take three readings at 2-minute intervals.

Secondary Outcomes

  • Perceived stress(3 Months)
  • Measure of Depressive Symptoms using the PHQ-8(3 Months)

Study Sites (1)

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