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Partner Notification of Sexually Transmitted Infections (STIs) in Testing Centers

Conditions
Hiv
STI
Interventions
Other: 2 online self-administered questionnaires on
Registration Number
NCT04921618
Lead Sponsor
ANRS, Emerging Infectious Diseases
Brief Summary

Since the 2000s, the incidence of bacterial STIs increases, mainly among men who have sex with men but also among heterosexual men and women with multiple sexual partners. A partner notification (PN) approach could break transmission chains and curb STI epidemics. PN brings together a set of interventions to help people diagnosed with STIs to inform their partners, encourage them to get tested, so that they can access treatment or prevention. A PN approach, systematically offered at STI diagnosis, has not yet been implemented in France and needs to be evaluated. In 2018, the Conseil National du Sida (French National AIDS Council) stated in favor of a formalized PN approach, particularly in testing centers, which carry out a large part of STI diagnoses.

The aim of our research project is to build interventions facilitating information, testing and treatment of partners of people diagnosed with STIs in testing centers and sexual health clinics.

Step 1: A cross-sectional study

Primary objective

To describe the PN practices of people diagnosed with an STI in testing centers and sexual health clinics without any intervention

Secondary objectives

* To describe the profiles of people diagnosed with an STI in testing centers or sexual health clinics and therefore likely to receive an intervention to help them notify their partners;

* To describe the profiles of people notified by their partners and who attend testing centers or sexual health clinics for STI testing;

* To describe the notification received by these notified partners and identify the facilitators of testing use following notification.

Step 2: A qualitative study

Objectives

* To evaluate the acceptability of testing center staff for an STI notification program in general and discuss the feasibility of interventions pre-identified by a literature review;

* In a collaborative (researchers and staffs) approach, to adapt these interventions to (1) the testing centers working and (2) the needs of their users identified in the cross-sectional study.

Expected results

This study is the first step in implementation of a PN program as part of a comprehensive management of STI diagnoses in France.

Detailed Description

Methods

Step 1: A cross-sectional study

Cross-sectional study conducted in testing centers and sexual health clinics (6 centers, 6 months of enrollment), targeting two populations:

* People aged 18 years or more diagnosed for at least one STI: the index patients;

* People aged 18 years or more attending the same centers for STI testing after being notified by a sexual partner: the notified partners.

This study is based on 3 online self-administered questionnaires:

* A questionnaire, the same for index patients and notified partners, collecting socio-demographic profile, health care and testing use, STI history and sexual behavior;

* A questionnaire for index patient on spontaneous PN practices of index patients one month after STI diagnosis, including types of partners notified, methods used to notify, and reasons for not notifying partners (this questionnaire will be sent one month after STI diagnosis to give participants the time to inform their partners);

* A questionnaire for notified partner on their experience of PN, such as the type of notifying partner, the methods and information transmitted during notification, their feelings and what led them to get testing after being notified.

A notified partner diagnosed with an STI will receive also the questionnaire on spontaneous practices of index patients at M1. This will allow us to observe whether people who had already been notified for an STI are more likely to notify their partners.

Step 2: A qualitative study

Focus-groups of 6-8 volunteers involved in STI testing in testing centers and sexual health clinics will be conducted based on an interview guide. Doctors and other staffs will be interviewed separately.

Thematic analysis

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
2200
Inclusion Criteria

For index patients

  • Diagnosed with at least one bacterial STI, and/or HIV and/or acute HCV at one of the participating centers during the study period,
  • Aged >= 18,
  • Agree to participate in the study after oral and written information.

For notified partners

  • Attend one of the participating centers during the study period, within 6 months of being notified of their exposure to an STI (bacterial STI, and/or HIV and/or acute HCV) by one of their partners, who is infected with one or more of these STIs,
  • Aged >= 18,
  • Agree to participate in the study after oral and written information.

Non-Inclusion Criteria:

For index patients and notified partners

  • People who do not read or speak French,
  • Wardship or curatorship adults.
Read More
Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Notified partners2 online self-administered questionnaires onPeople aged 18 or more getting STI testing in testing centers after being notified by a sexual partner. \[STI = bacterial STIs and/or HIV and/or acute HCV\]
Index patients2 online self-administered questionnaires onPeople aged 18 or more diagnosed with \>= 1 STI in testing centers. \[STI = bacterial STIs and/or HIV and/or acute hepatitis C virus (HCV)\]
Primary Outcome Measures
NameTimeMethod
Partner notification by index patientsOne month after STI diagnosis

Proportion of index patients who notified at least one sexual partner one month after their STI diagnosis

Secondary Outcome Measures
NameTimeMethod
Partners notified by index patientsOne month after STI diagnosis

Mean proportion of notified partners among partners reported by index patients

Notified partners tested positiveAt notified partners inclusion

Proportion of notified partners tested positive among notified partners attending STI testing

Trial Locations

Locations (9)

CeGIDD d'Aix-en-Provence

🇫🇷

Aix-en-Provence, France

CeGIDD - Saint Adrien

🇫🇷

Marseille, France

CeGIDD de Lille

🇫🇷

Lille, France

CeGIDD de Bichât

🇫🇷

Paris, France

CeGIDD de Caen

🇫🇷

Caen, France

Centre de santé sexuelle - LE 190

🇫🇷

Paris, France

CeGIDD - La Joliette

🇫🇷

Marseille, France

CeGIDD de La Pitié Salpêtrière

🇫🇷

Paris, France

Institut Alfred Fournier

🇫🇷

Paris, France

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