PET Scan as a Screening Tool for Liver Transplant in Patients With HCC
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 100
- Locations
- 2
- Primary Endpoint
- Overall Survival
Study Overview
Brief Summary
This study aims at testing the utility of PET Scan as a screening tool for liver transplantation in patients with Hepatocellular Carcinoma. Patients being worked up for liver transplant for hepatocellular carcinoma will undergo a PET Scan and will be followed until 2 years after transplantation. At that time survival data will be analysed according to PET Scan results to determine if it can be used to predict outcome.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Male or female patient over 18 years of age
- •Diagnosis of HCC confirmed by histology if available or by two imaging modalities
- •Able to give written informed consent prior to any study specific screening procedures with the understanding that the patient has the right to withdraw from the study at any time, without prejudice.
Exclusion Criteria
- •Unable to give consent to the study
- •Unable to undergo a PET Scan
Outcomes
Primary Outcomes
Overall Survival
Time Frame: up to death
The primary objective of the study is to compare, according to PET scan results, the post-transplantation overall survival of patients meeting Milan criteria to those not meeting Milan criteria
Secondary Outcomes
No secondary outcomes reported
Investigators
peter metrakos
Director Multiorgan Transplant Program-MUHC
McGill University Health Centre/Research Institute of the McGill University Health Centre