PRINTO (the Paediatric Rheumatology International Trials Organisation)
- Conditions
- Juvenile Idiopathic Arthritis
- Registration Number
- NCT00415935
- Lead Sponsor
- Institute of Child Health
- Brief Summary
A comparison of outcome in children with JIA who are in remission on MTX, when MTX is then stopped for either 6 or 12 months
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Any child with JIA who has gone into remission using methotrexate
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the long-term outcomes of discontinuing methotrexate in JIA remission as studied in NCT00415935?
How does methotrexate withdrawal affect disease relapse rates in different JIA subtypes?
What biomarkers correlate with sustained remission in JIA patients after methotrexate cessation?
Are there specific molecular pathways influenced by methotrexate discontinuation in pediatric rheumatology?
What management strategies are effective for adverse events following methotrexate stoppage in JIA trials?
Trial Locations
- Locations (1)
Rheumatology ICH
🇬🇧London, United Kingdom
Rheumatology ICH🇬🇧London, United KingdomLucy Wedderburn, DrContactl.wedderburn@ich.ucl.ac.uk