Effects of Ramadan Diurnal Fasting Combined With a Structed Aerobic Exercise on Body Composition and Cardiometabolic Health in Adults With Overweight and Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Total body fat mass
研究概览
简要总结
The goal of this interventional study is to examine the effects of Ramadan diurnal fasting alone and in combination with moderate-intensity aerobic exercise on cardiometabolic health in adults with overweight and obesity. The main questions it aims to answer are:
- Does Ramadan diurnal fasting lead to changes in body composition and cardiometabolic health outcomes?
- Does adding moderate-intensity aerobic exercise during Ramadan fasting result in greater improvements in cardiometabolic health compared with fasting alone?
Participants will be randomly assigned to one of two groups: Ramadan diurnal fasting only or Ramadan diurnal fasting combined with a supervised moderate-intensity aerobic exercise program. Cardiometabolic, metabolic, and behavioral outcomes will be assessed before Ramadan and during the last week of Ramadan.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
This is an open-label study; no participants, investigators, or outcome assessors are masked due to the nature of the fasting and exercise intervention.
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 20-60
- •Body mass index (BMI) ≥27 kg/m²
- •Planning to observe Ramadan diurnal fasting for the duration of Ramadan
排除标准
- •Diagnosed cardiovascular, metabolic, renal, or endocrine disease (e.g., diabetes, cardiovascular disease)
- •Use of medications known to affect metabolism, glucose regulation, or lipid metabolism
- •Current smoking or use of nicotine products
- •Pregnancy or breastfeeding
研究组 & 干预措施
Ramadan diurnal fasting only group (RDF)
Participants observe Ramadan diurnal fasting without a structured exercise program.
Ramadan Fasting + Exercise
Participants observe Ramadan diurnal fasting and participate in a supervised moderate-intensity aerobic exercise program performed approximately 5 days per week during the fasting period.
干预措施: Moderate-Intensity Aerobic Exercise (Behavioral)
结局指标
主要结局
Total body fat mass
时间窗: From enrollment to the end of the month of Ramadan (week 10)
Total body fat mass in kilogram will be assessed using dual-energy X-ray absorptiometry (DEXA)
次要结局
- Glycemic control(From enrollment to the end of the month of Ramadan (week 10))
- Lipids profile(From enrollment until the end of the month of Ramadan (week 10))
- Resting metabolic rate(From enrollment until the end of the month of Ramadan (week 10))
- Circulating concentrations of interleukin-6 (IL-6)(From enrollment until the end of the month of Ramadan (week 10))
- Tumor necrosis factor-alpha (TNF-α)(From enrollment until the end of the month of Ramadan (week 10))
研究者
Abdullah Alwaleedi
Graduate Student Research Assistant
University of Michigan