NCT04340414Unknown不适用
Safety and Effectiveness Study of Low Flow Extracorporeal Membrane Oxygenation（CO2 Removal） Driving by Continuous Hemofiltration Machine the Severe New Corovirus Pneumonia (NCP)
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- PaCO2
研究概览
简要总结
assess the safety and effectiveness of using low-flow extracorporeal membrane oxygenation(CO2 removal) driving by CVVH machine in the severe NCP patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •NCP with severe acute respiratory distress syndrome with ratio of partial pressure of arterial oxygen over fraction of inspired oxygen (PaO2:FiO2)<150 and PEEP >10cmH2O
- •Driving pressure> 20cmH2O
- •4.PaCO2>55cmH2O and/or PH>7.3
排除标准
- •poor venous vascular condition and unavaible for central venous catheter placement
研究组 & 干预措施
NCP patient with severe ARDS and/or high ventilator supported
Experimental
The NCP patient with severe ARDS and/or high ventilator supported condition was eligibilitable for enrollment
干预措施: Low flow ECMO driving by CVVH machine (Device)
结局指标
主要结局
PaCO2
时间窗: Day 1
PaCO2 from blood gas analysis
Tidal volume
时间窗: Day 1
Tidal volume monitor by ventilator
Driving Pressure
时间窗: Day 1
Driving Pressure monitor by ventilator
次要结局
未报告次要终点
研究者
研究点 (1)
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