The effects of adding letrozole to methotrexate on the management of tubal ectopic pregnancies

Not Applicable

• Conditions: Tubal ectopic pregnancy.; Tubal pregnancy; O00.1

• Registration Number: IRCT20130808014301N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 July 2020

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

Tubal ectopic pregnancies
BetaHCG level less than 5000 IU/

Exclusion Criteria

Fetal heart rate
Hemodynamic instability
Significant abdominal pain
History of allergic reactions to methotrexate
History of allergic reactions to letrozole and other aromatase inhibitor agents
hypercholesterolemia
Liver enzymes abnormalities
Abnormal renal function tests
Heterotopic pregnancies

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood beta-HCG level changes. Timepoint: Before, and 4 and 7 days after beginning of the treatment, then weakly until the negative test. Method of measurement: blood test.