The effect of combined aerobic exercise with upper limb therapy on central nervous system growth factors and the manual dexterity of individuals after stroke

Not Applicable

Recruiting

• Conditions: Stroke, not specified as hemorrhagic or ischemic; Sequelae of stroke not specified as hemorrhagic or ischemic; I69.4

• Registration Number: RBR-3jhzz3
• Lead Sponsor: niversidade Federal de São Carlos - UFSCar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-09
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Individuals with hemiparesis who present the last episode of stroke (ischemic or hemorrhagic) for more than 6 months (chronic phase after stroke). Individuals with more than one stroke may be included as long as the insult involves the same hemisphere. Only individuals who have strokes involving the territories of the middle and anterior cerebral arteries will be included. Individuals must submit a referral, imaging tests and medical report with the diagnosis of stroke. The age range should be between 35 and 80 years.
As a criterion for the implementation of the ICM protocol, all participants should present a minimum active movement of 45 ° of flexion and abduction of the shoulder, 20 ° of elbow extension, 10 ° of wrist extension, 10 ° of abduction or extension of the thumb , and 10 ° extension in at least two fingers (metacarpophalangeal and interphalangeal joints) beyond the thumb.
In addition, they should show asymmetry in the use of the upper limbs with a score of ? 2.5 in the Motor Activity Log quantity scale. For the proposed activities, individuals should be able to remain in the seated posture without trunk and arms support 1 minute.

Exclusion Criteria

individuals with cognitive deficits according to the Mental State Mini Exam (score less than 13 for illiterate individuals, 18 for individuals with 1 to 7 years of study, and 26 for individuals with more than 8 years of study); individuals smokers, alcohol users, users of illicit drugs; individuals with structural abnormalities in cardiovascular systems such as hypertrophic cardiomyopathy, aortic aneurysm, left bundle branch block; and respiratory; individuals with uncorrected auditory and visual deficits; electrocardiogram (ECG) abnormalities such as ischemic changes, arrhythmias (atrial fibrillation, atrial flutter), conduction disorders, both at rest and during the clinical exercise test, to be lauded by a cardiologist. In addition, individuals with historical diseases or osteomioarticular alterations that prevent the performance of the procedures or generate pain during the activities, obese (BMI> 28 kg / m2), with diabetes and uncontrolled hypertension, comprehension aphasia, apraxia, stroke bilateral, acute or subacute (<6 months) stroke, transient vascular accident and other central and peripheral nervous system diseases and / or insult due to HIV. Also not included are individuals who are participating in other experimental or rehabilitation studies and who have had botulinum toxin application in the last three months prior to evaluation.

Individuals will have their participation interrupted in the study, if they present pain during the procedures, changes such as postural hypotension, angina, marked alteration of blood pressure (PAsystolic <100 mmHg or> 160 mmHg and PAdiastolic <60 mmHg or> 110 mmHg) or frequency (HR max = 220-age - men or 210-age women), as well as peripheral oxygenation <90% or perception of dyspnea on the BORG> 15 scale (0-20)

Study & Design

• Study Type: Intervention
• Study Design: Not specified