Combined Effect of Action Observation and Motor Imagery on Motor Function of Lower Limb Among Patients with Acute Stroke: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Fugl-Meyer Assessment of Lower Extremity
研究概览
简要总结
Stroke is a major contributor to adult disability worldwide, often resulting in significant lower limb motor deficits that limit mobility, balance, and independence. While conventional physiotherapy remains the cornerstone of stroke rehabilitation, innovative neurorehabilitation techniques are gaining attention for their ability to promote brain plasticity. Action Observation (AO) and Motor Imagery (MI), two non-invasive, cognitive-based strategies, have independently shown potential to enhance motor recovery. However, limited evidence exists on the combined application of AO and MI in stroke rehabilitation, especially for the lower limbs. This randomized controlled trial investigates the synergistic effect of AO and MI, integrated with standard physiotherapy, on improving lower limb motor function in patients with acute stroke. The study aims to offer a novel, effective, and accessible intervention to accelerate functional recovery and restore independence in stroke survivors
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with MRI or CT-confirmed acute Anterior Cerebral Artery (ACA) stroke Stroke onset between 7 to 30 days prior to enrollment Presence of lower limb hemiplegia Age between 45 and 80 years Both male and female participants Glasgow Coma Scale (GCS) score of 10 or more out of 15 Montreal Cognitive Assessment (MoCA) score of 18 or higher, indicating stable cognition Brunnstrom Recovery Stage (BRS) between stage 3 and stage 5.
排除标准
- •MCA, PCA stroke Co-existing LL musculoskeletal disorders Other neurological or psychiatric disorders severe sensory deficits.
结局指标
主要结局
Fugl-Meyer Assessment of Lower Extremity
时间窗: Fugl-Meyer Assessment – Lower Extremity (FMAL-LE), a reliable performance-based scale to assess sensorimotor impairment post-stroke. Scored 0–2 per item, max score 34. Assessed pre- and post-intervention (at 3 weeks) to evaluate motor recovery.
次要结局
- Montreal Cognitive Assessment-MoCA(MoCA will be used pre intervention as a screening tool to assess cognition & orientation, essential for AOT & MI. It evaluates multiple cognitive domains with high sensitivity, specificity ensuring participants can follow instructions & differentiate imagined versus real actions)