Retroperıtoneal Soft-Tıssue Sarcomas

Not Applicable

Completed

• Conditions: Margin, Tumor-Free; Retroperitoneal Sarcoma
• Interventions: Procedure: retroperitoneal mass excision

• Registration Number: NCT05044624
• Lead Sponsor: Istanbul Medeniyet University

Brief Summary

: Soft Tissue Sarcomas are rare mesenchymal tumors with many subtypes. Clean margin-wide resection is recommended for treatment. The guidelines recommend that sarcoma treatments be carried out in sarcoma centers. In this study, the location, histopathological features, clinical and demographic features, recurrence, and prognosis of retroperitoneal sarcomas were investigated.

Detailed Description

The demographic, histopathological, and immunohistochemical data of the patients who were operated on with the diagnosis of intraabdominal mass at Istanbul Medeniyet University Göztepe Prof. Dr. Süleyman Yalçın City Hospital from March 2016 to December 2020 were retrospectively evaluated. Ethical approval was obtained from Istanbul Medeniyet University Göztepe Prof. Dr. Süleyman Yalçın City Hospital Ethics Committee.

Patients diagnosed with pathological sarcoma subclass were included in the study. Patients younger than 18 years were excluded from the study. Visceral organ-origin sarcomas and extremity sarcomas were also excluded from the study. GIST's were included in sarcoma subtypes by WHO in 2013. However, they were not included in the study due to their solid organ origin.

The data of 18 patients' whore remained after the exclusion criteria were analyzed retrospectively. Pathology samples of the patients were re-examined by a single pathologist.

The demographic analysis was used for statistics.

Study Timeline

• Study Start: 2016-03-01
• Primary Completion: 2021-06-01
• Study Completion: 2021-06-01
• Status Verified: 2021-09
• Study First Submitted: 2021-09-02
• Study First Submitted QC: 2021-09-09
• Last Update Submitted: 2021-09-09
• Study First Posted: 2021-09-16
• Last Update Posted: 2021-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Patients operated with the diagnosis of intra-abdominal mass
• patients diagnosed with pathological sarcoma subclasses

Exclusion Criteria

• Patients younger than 18 years
• Visceral organ-origin sarcomas
• extremity sarcomas
• GIST

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Margin, Tumor-Free	retroperitoneal mass excision	-

Primary Outcome Measures

Name	Time	Method
Clean margin wide resection	63 month	effect of clean surgical margin on recurrence