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Mindfulness in Hidradenitis Suppurativa

Not Applicable
Completed
Conditions
Hidradenitis Suppurativa
Registration Number
NCT06123429
Lead Sponsor
University of Arkansas
Brief Summary

The study will investigate the impact of an 8-week-long Mindfulness-Based Stress Reduction course on quality of life and disease severity in patients with hidradenitis suppurativa (HS).

Detailed Description

This is a voluntary 8-week-long, non-medical intervention study for patients with hidradenitis suppurativa (HS). This study will enroll participants in an 8-week-long Mindfulness-Based Stress Reduction course and observed for any changes in validated measures of quality of life. Quality of life scores will be evaluated via multiple surveys including the Dermatology Quality of Life index, HS Quality of Life index, GAD7, and PHQ9. Surveys will be collected Week 1 of 8 week MBSR course intervention; Week 4; End of MBSR Course at week 8; and Week 12. The first goal is to investigate the effectiveness of the addition of mindfulness-based stress reduction (MBSR) intervention to conventional medical treatment on improving mental health in HS participants. The second goal is to assess participant preference for MBSR intervention.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
25
Inclusion Criteria
  • This study will only enroll subjects between the ages of 18-years and 89-years of age.
  • Diagnosis of HS
  • Able to read and comprehend study materials in English, ie: surveys
Exclusion Criteria
  • Those who do not fit inclusion criteria
  • Non-English speaking
  • Patient who recently began any psychotropic medication within 3 months prior to the baseline evaluation visit.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Dermatology Quality of Life Index (DLQI scores)Week 1 of 8 week MBSR course intervention; Week 4; End of MBSR Course at week 8; and Week 12

Change in DLQI scores before and after Mindfulness Based Stress Reduction course.

DLQI score interpretation:

0 - 1 no effect at all on patient's life 2 - 5 small effect on patient's life 6 - 10 moderate effect on patient's life 11 - 20 very large effect on patient's life 21 - 30 extremely large effect on patient's life

Generalized Anxiety Disorder (GAD7)Week 1 of 8 week MBSR course intervention; Week 4; End of MBSR Course at week 8; and Week 12.

Change in GAD7 scores before and after Mindfulness Based Stress Reduction course. This is calculated by assigning scores of 0, 1, 2, and 3 to the response categories, respectively, of "not at all," "several days," "more than half the days," and "nearly every day." GAD-7 total score for the seven items ranges from 0 to 21. 0-4: minimal anxiety 5-9: mild anxiety 10-14: moderate anxiety 15-21: severe anxiety

Patient Health Questionaire (PHQ9)Week 1 of 8 week MBSR course intervention; Week 4; End of MBSR Course at week 8; and Week 12.

Change in PHQ9 scores before and after Mindfulness-Based Stress Reduction course.

Scoring: add up all checked boxes on PHQ-9 For every 3 Not at all = 0; Several days = 1; More than half the days = 2; Nearly every day = 3 Interpretation of Total Score

Total Score Depression Severity 1-4 Minimal depression 5-9 Mild depression 10-14 Moderate depression 15-19 Moderately severe depression 20-27 Severe depression

Secondary Outcome Measures
NameTimeMethod
Hidradenitis Suppurativa Quality of Life Index (HiSQOL)Week 1 of 8 week MBSR course intervention; Week 4; End of MBSR Course at week 8; and Week 12.

Change in HiSQOL scores before and after Mindfulness-Based Stress Reduction course.

Grading:

Not at all = 0 points Slightly = 1 point Moderately = 2 points Very much = 3 points Extremely = 4 points

0-17 = No effect 18-34 = Small effect 35-51 = Moderate effect 52-68 = Severe effect

Max score = 68 points

Trial Locations

Locations (1)

UAMS Dermatology Clinic

🇺🇸

Little Rock, Arkansas, United States

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