Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020

• Conditions: Atrial Fibrillation; Stroke Prevention

• Registration Number: NCT04686045
• Lead Sponsor: Jan Kochanowski University

Brief Summary

Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K antagonist oral anticoagulants (NOACs) over therapy with vitamin K antagonists (VKA) in most AF patients. The number of patients treated with NOACs has increased significantly during the last few years. In the primary randomized controlled trials leading to their approval, compared to warfarin, NOACs were shown to be either noninferior or superior for stroke prevention in AF, with similar or reduced rates of bleeding, especially intracranial haemorrhage.

The aim of this study was to assess the frequency of oral anticoagulants using, espescially apixaban, dabigatran, and rivaroxaban, and the predictors of their prescription in a group of hospitalised patients with AF.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-12-22
• Study First Submitted QC: 2020-12-22
• Study First Posted: 2020-12-28
• Status Verified: 2021-01
• Study Start: 2021-01-01
• Last Update Submitted: 2021-01-24
• Last Update Posted: 2021-01-26
• Primary Completion: 2021-03-01
• Study Completion: 2021-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• non-valvular atrial fibrillation

Exclusion Criteria

• valvular atrial fibrillation
• death during hospitalization

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
oral anticoagulant treatment	one year

Trial Locations

Locations (2)

Iwona Gorczyca; 🇵🇱 Kielce, Poland

1st Clinic of Cardiology and Electotherapy; 🇵🇱 Kielce, Grunwaldzka 45, Poland