NCT00065624CompletedPhase 2
Antioxidant Functions of Lipoic Acid
National Center for Complementary and Integrative Health (NCCIH)1 site in 1 country16 target enrollmentStarted: November 1, 2003Last updated:
Conditions
Drugs
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Enrollment
- 16
- Locations
- 1
Study Overview
Brief Summary
The goal of this study is to determine whether a short treatment with lipoic acid, an antioxidant used in the treatment of diabetic neuropathy, improves blood vessel reactivity and decreases oxidant stress in persons with elevated blood cholesterol.
Detailed Description
As per Brief Summary
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double
Eligibility Criteria
- Ages
- 50 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Lipid criteria for inclusion are a plasma LDL between 160 and 190 mg/dl (total cholesterol usually 240-285 mg/dl)
- •Less than 2 coronary risk factors, and already on a cholesterol-lowering diet.
Exclusion Criteria
- •Overt or clinical atherosclerosis
- •Currently taking cholesterol-lowering medication.
- •Subjects with other lipid disorders
- •Subjects taking supplemental lipoic acid, vitamin C, or vitamin E.
Investigators
Study Sites (1)
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