The effect of pomegranate juice and exercise on prostate cancer
Phase 1
- Conditions
- prostate cancer.
- Registration Number
- IRCT20200901048588N1
- Lead Sponsor
- Khoram-Abad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 60
Inclusion Criteria
Failure to perform radiation therapy, chemotherapy and androgen therapy
Do not perform any surgery
> PSA 6 as a benchmark for the study process
Lack of continuous exercise before starting the exercise program
Exclusion Criteria
Perform specialized treatments such as chemotherapy and radiation therapy in the last 6 months
Perform prostate cancer related surgeries
having cardiovascular disease, diabetes and neurological diseases
Alcohol consumption, smoking
Cancer cell metastasis and involvement of other tissues and organs in the body
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MicroRNA-21,microRNA-34,microRNA-155. Timepoint: 48 hours before and after eight weeks of aerobic exercise and consumption of pomegranate juice. Method of measurement: Real time-PCR device.
- Secondary Outcome Measures
Name Time Method Prostate-Specific Antigen (PSA),Superoxide dismutase(SOD),Glutathione peroxidase(GPX),Malondialdehyde(MDA). Timepoint: 48 hours before and after the performance, eight weeks of aerobic training and consumption of pomegranate juice. Method of measurement: ELISA device.