To evaluate skin hydration and tolerance, after application, of 3 test product creams containing Dexpanthenol 5% and Allantoin 0.5% in 3 different base formulations, on inner forearms , over duration of 24 hours.

Not Applicable

Completed

• Registration Number: CTRI/2013/06/003765
• Lead Sponsor: Dr Reddys Laboratories Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2013-06-20
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

a)Voluntary women/men between 18-45 years.

b)Having signed a Consent Form after the trial has been explained orally and in writing, of all information concerning the study procedures and study objectives.

c)Dry skin type (Clinical evaluation followed by MoistureMeter SC Readings which should be < 18).

d)Presenting healthy skin on test sites.

e)Cooperating, informed of the need and duration of the examinations

Exclusion Criteria

a)Menopausal/Pregnant women by taking history.

b)Allergic to any cosmetic product.

c)A volunteer who the Investigator feels will not be compliant with trial requirements.

d)Any type of skin disorder which investigator feels will interfere with the study

e)Subjects on any medical treatment either systemic or topical which may interfere with the performance of the study treatment (presently or in the past 1 month). E.g. topical steroids.

f)Chronic illness which may influence the skin sensitivity (skin problems like atopic dermatitis, psoriasis, eczema or diseases like hypothyroidism, anemia, hormonal problems or patients on anti cholesterol drugs, etc)

g)Any cutaneous disease which would predispose to dry skin (confirmed by prior history).

h)Any cutaneous conditions on test site (scars, moles, papules etc).

i)Women having their menstrual cycle during the study.

j)Subject in an exclusion period or already participating in another similar cosmetic or therapeutic trial as identified during screening on visit 1 (V1).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hydration measurements using the instrument Moisture Meter SC Compact. <br/ ><br>ï?? <br/ ><br> <br/ ><br>Transepidermal water Loss measurements using the instrument VapometerTimepoint: 0 hour, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours and 24 hours

Secondary Outcome Measures

Name	Time	Method
Clinical examination of skin for local reactions, if anyTimepoint: over duration of 24 hours