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Clinical Trials/NCT03913611
NCT03913611
Active, not recruiting
Not Applicable

A Randomised Controlled Trial of Accelerated Rehabilitation Versus Standard Rehabilitation After Double-row Rotator Cuff Repair. Does Rehabilitation Regimen Affect Clinical Outcomes?

Manchester University NHS Foundation Trust1 site in 1 country50 target enrollmentOctober 18, 2019

Overview

Phase
Not Applicable
Intervention
Traditional rehabilitation protocol
Conditions
Rotator Cuff Tear
Sponsor
Manchester University NHS Foundation Trust
Enrollment
50
Locations
1
Primary Endpoint
Oxford Shoulder Score
Status
Active, not recruiting
Last Updated
2 months ago

Overview

Brief Summary

This is a randomised controlled trial involving patients who have a double-row arthroscopic rotator cuff repair.

Null hypothesis: There is no difference in outcome between standard rehabilitation and accelerated rehabilitation after arthroscopic rotator cuff repair.

Following surgery, they will be randomised to one of two groups:

  1. Standard rehabilitation, with enforced sling use for 6 weeks and a structured exercise programme.
  2. Accelerated rehabilitation with no requirement to use a sling and a structured exercise programme.

The primary outcome measure will be the Oxford Shoulder Score at 6 months. We will also collect data on postoperative pain, range of shoulder movement and other subjective outcome measures. All patients will have MRI scans at 6 months postoperatively to assess the integrity of the repair, allowing comparison of failure rates between groups.

Detailed Description

This is a randomised controlled trial involving patients who have a double-row arthroscopic rotator cuff repair. We wish to compare clinical and radiological outcomes for patients undergoing standard rehabilitation protocols versus accelerated rehabilitation. A double-row repair will be used in this study as it has been shown in laboratory testing to be stronger and withstand significantly more cyclical loads before failure. Patients who have failed conservative treatment for their rotator cuff tears will be offered inclusion in the study. Baseline scores and measurements will be taken prior to surgery. After a successful surgical repair has been confirmed, patients will be randomised to one of two rehabilitation programmes. One programme will mandate use of a sling for 6 weeks, and another will not require use of a sling after the immediate postoperative period. All patients will be followed up for one year, at intervals of 6 weeks, 3 months, 6 months and 12 months, using subjective outcome measures, objective measures of movement and an MRI scan to assess the integrity of the repair at 6 months.

Registry
clinicaltrials.gov
Start Date
October 18, 2019
End Date
December 31, 2026
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adults aged over 40 with a degenerate full-thickness posterosuperior rotator cuff tear undergoing arthroscopic rotator cuff repair (+/- concomitant procedures such as biceps tenotomy and subacromial decompression).

Exclusion Criteria

  • Other musculoskeletal disease affecting same limb
  • Massive rotator cuff tear
  • Subscapularis tear
  • Incomplete cuff repair
  • Repair under tension
  • Non-English speaker
  • Inability to follow postoperative instructions / restrictions

Arms & Interventions

Traditional Rehabilitation

In this arm, patients will undergo the standard rehabilitation protocol, with sling use for 6 weeks.

Intervention: Traditional rehabilitation protocol

Accelerated Rehabilitation

In this arm, patients will undergo the accelerated rehabilitation protocol, with no sling use outside the immediate postoperative period.

Intervention: Accelerated rehabilitation protocol

Outcomes

Primary Outcomes

Oxford Shoulder Score

Time Frame: 3 months

A validated patient-reported outcome measure of shoulder function. This score ranges from 0-48, with higher scores representing a better outcome.

Secondary Outcomes

  • Range of shoulder movement(6 weeks, 3 months, 6 months, 12 months postoperatively.)
  • Oxford Shoulder Score(6 weeks, 3 months, 6 months, 12 months postoperatively.)
  • EQ5D(6 weeks, 3 months, 6 months, 12 months postoperatively.)
  • Postoperative pain score(6 weeks)
  • Shoulder Pain and Disability Index(6 weeks, 3 months, 6 months, 12 months postoperatively.)
  • Structural integrity of repair(6 months.)

Study Sites (1)

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