JPRN-UMIN000012032已完成1 期
Phase Ib study of 131I-metaiodobenzylguanidine(MIBG) therapy with Valproic Acid(VPA) for high risk or recurrent neuroblastoma - Phase Ib study of VPA and 131I-MIBG for recurrent / resistant neuroblastoma
ational Cancer Research Center Hospital0 个研究点目标入组 10 人开始时间: 2013年10月14日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 3years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. active double cancer(synchronous double cancer and metachronous double cancer within 5 disease -free years),excluding carcinoma In situ(lesions equal to Intraepithelial or intramucosal Cancer)judged to have been cured with local treatment 2. active infection requiring systemic medication 3. abnormality in electrocardiogram tested within 28 days,requiring intervention 4. Psychosis which is not appropriate for participating in this study
研究者
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A Phase I study of 131-I mIBG followed by Nivolumab and Dinutuximab beta Antibodies in children with relapsed/refractory Neuroblastoma.Relapsed or refractory high risk neuroblastomaMedDRA version: 20.0Level: PTClassification code 10029260Term: NeuroblastomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2016-002221-11-DEniversity Hospital Southampton NHS Foundation Trust (UK)36