ISRCTN31549735已完成未知
Cross-sectional surveillance study on pneumococcal carriage to establish a baseline before putative introduction of more-valent pneumococcal conjugate vaccine and to assess the impact of 2 years of SARS-CoV-2 containment measures on immunity and carriage of S. pneumonia and other microbes.
ational Institute for Public Health and the Environment0 个研究点目标入组 660 人开始时间: 2023年2月16日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 660
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. The children have to be of normal health (same health criteria apply as used in well-baby clinics when a child receives a vaccination, e.g. also children with small increases in temperature or cold are seen as children with normal health, fever >38.5°C in the last two days is not considered as normal health)
- •2. The parents/legal guardians have to be willing and able to participate in the trial according to procedure
- •3. The child is 24-months-old (± 4 weeks)
- •4. The child has been vaccinated according to the Dutch NIP
- •5. Presence of a signed informed consent (the parents/legal guardians have given written informed consent after receiving oral and written information)
- •6. Parents/legal guardians of 24-month-old children are included when the child fulfils the inclusion criteria and sign their own informed consent
排除标准
- •A potential participating child who meets any of the following criteria will be excluded from participation in this study:
- •1. Previous vaccinations with PCV using a vaccine and schedule that differs from the Dutch NIP of that age group
- •2. Medical conditions that will severely affect immunological responses to vaccinations or nasopharyngeal carriage rates (certain chromosomal abnormalities or craniofacial abnormalities (like Trisomy 21 or schisis), known or suspected immunodeficiency disease or other medical conditions)
- •A parent/legal guardian who meets any of the following criteria will be excluded from participation in this study:
- •3. Medical conditions that will severely affect immunological responses to vaccinations or nasopharyngeal carriage rates (certain chromosomal abnormalities or craniofacial abnormalities (like Trisomy 21 or schisis), known or suspected immunodeficiency disease or other medical conditions)
研究者
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