Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
- Conditions
- Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorAskin TumorMetastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Interventions
- Other: Laboratory Biomarker Analysis
- Registration Number
- NCT00899990
- Lead Sponsor
- Children's Oncology Group
- Brief Summary
This research study is collecting and storing samples of tumor tissue, bone marrow, and blood from patients with Ewing sarcoma. Collecting and storing samples of tumor tissue, bone marrow, and blood from patients with cancer to test in the laboratory may help the study of cancer in the future.
- Detailed Description
OBJECTIVES:
I. Collect biological specimens, including associated demographic and clinical data, from patients with Ewing sarcoma.
II. Provide a repository for long-term storage of Ewing sarcoma-related biological materials.
III. Make collected specimens available to qualified researchers to understand the biology of Ewing sarcoma and correlate these results with demographic and clinical data.
OUTLINE: This is a multicenter study.
Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 908
-
Diagnosis of Ewing sarcoma, including peripheral primitive neuroectodermal tumor and Askin tumor
- Newly diagnosed or recurrent disease
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Observational (biomarker sampling) Laboratory Biomarker Analysis Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.
- Primary Outcome Measures
Name Time Method Banking of biological specimens, including associated demographic and clinical data Not Provided
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (189)
Children's Hospital of Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
University of Maryland/Greenebaum Cancer Center
🇺🇸Baltimore, Maryland, United States
Saint Christopher's Hospital for Children
🇺🇸Philadelphia, Pennsylvania, United States
Johns Hopkins University/Sidney Kimmel Cancer Center
🇺🇸Baltimore, Maryland, United States
Advocate Children's Hospital-Park Ridge
🇺🇸Park Ridge, Illinois, United States
Kingston Health Sciences Centre
🇨🇦Kingston, Ontario, Canada
Eastern Maine Medical Center
🇺🇸Bangor, Maine, United States
West Virginia University Charleston Division
🇺🇸Charleston, West Virginia, United States
Hospital for Sick Children
🇨🇦Toronto, Ontario, Canada
Allan Blair Cancer Centre
🇨🇦Regina, Saskatchewan, Canada
Children's Hospital Los Angeles
🇺🇸Los Angeles, California, United States
Cedars Sinai Medical Center
🇺🇸Los Angeles, California, United States
Mattel Children's Hospital UCLA
🇺🇸Los Angeles, California, United States
UCLA / Jonsson Comprehensive Cancer Center
🇺🇸Los Angeles, California, United States
Valley Children's Hospital
🇺🇸Madera, California, United States
Nationwide Children's Hospital
🇺🇸Columbus, Ohio, United States
Children's Hospital of Pittsburgh of UPMC
🇺🇸Pittsburgh, Pennsylvania, United States
Lurie Children's Hospital-Chicago
🇺🇸Chicago, Illinois, United States
University of Illinois
🇺🇸Chicago, Illinois, United States
Rainbow Babies and Childrens Hospital
🇺🇸Cleveland, Ohio, United States
Cleveland Clinic Foundation
🇺🇸Cleveland, Ohio, United States
Lee Memorial Health System
🇺🇸Fort Myers, Florida, United States
Children's Hospital and Research Center at Oakland
🇺🇸Oakland, California, United States
Miller Children's and Women's Hospital Long Beach
🇺🇸Long Beach, California, United States
Connecticut Children's Medical Center
🇺🇸Hartford, Connecticut, United States
Seattle Children's Hospital
🇺🇸Seattle, Washington, United States
Massachusetts General Hospital Cancer Center
🇺🇸Boston, Massachusetts, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center
🇺🇸Miami, Florida, United States
Miami Cancer Institute
🇺🇸Miami, Florida, United States
Riley Hospital for Children
🇺🇸Indianapolis, Indiana, United States
Saint Vincent Hospital and Health Care Center
🇺🇸Indianapolis, Indiana, United States
University Medical Center of Southern Nevada
🇺🇸Las Vegas, Nevada, United States
Nevada Cancer Research Foundation CCOP
🇺🇸Las Vegas, Nevada, United States
Sunrise Hospital and Medical Center
🇺🇸Las Vegas, Nevada, United States
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
🇺🇸Las Vegas, Nevada, United States
Rady Children's Hospital - San Diego
🇺🇸San Diego, California, United States
Naval Medical Center -San Diego
🇺🇸San Diego, California, United States
Children's Hospitals and Clinics of Minnesota - Minneapolis
🇺🇸Minneapolis, Minnesota, United States
University of Minnesota/Masonic Cancer Center
🇺🇸Minneapolis, Minnesota, United States
Duke University Medical Center
🇺🇸Durham, North Carolina, United States
Methodist Children's Hospital of South Texas
🇺🇸San Antonio, Texas, United States
University of Texas Health Science Center at San Antonio
🇺🇸San Antonio, Texas, United States
UCSF Medical Center-Mission Bay
🇺🇸San Francisco, California, United States
UCSF Medical Center-Parnassus
🇺🇸San Francisco, California, United States
Vanderbilt University/Ingram Cancer Center
🇺🇸Nashville, Tennessee, United States
Primary Children's Hospital
🇺🇸Salt Lake City, Utah, United States
Wayne State University/Karmanos Cancer Institute
🇺🇸Detroit, Michigan, United States
Ascension Saint John Hospital
🇺🇸Detroit, Michigan, United States
University of Oklahoma Health Sciences Center
🇺🇸Oklahoma City, Oklahoma, United States
University of Alabama at Birmingham Cancer Center
🇺🇸Birmingham, Alabama, United States
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center
🇺🇸Denver, Colorado, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Legacy Emanuel Children's Hospital
🇺🇸Portland, Oregon, United States
Legacy Emanuel Hospital and Health Center
🇺🇸Portland, Oregon, United States
Oregon Health and Science University
🇺🇸Portland, Oregon, United States
Tampa General Hospital
🇺🇸Tampa, Florida, United States
Children's Hospital Colorado
🇺🇸Aurora, Colorado, United States
Saint Joseph's Hospital/Children's Hospital-Tampa
🇺🇸Tampa, Florida, United States
Walter Reed National Military Medical Center
🇺🇸Bethesda, Maryland, United States
Children's Hospital and Medical Center of Omaha
🇺🇸Omaha, Nebraska, United States
University of Nebraska Medical Center
🇺🇸Omaha, Nebraska, United States
Scott and White Memorial Hospital
🇺🇸Temple, Texas, United States
Dana-Farber Cancer Institute
🇺🇸Boston, Massachusetts, United States
CancerCare Manitoba
🇨🇦Winnipeg, Manitoba, Canada
University of Hawaii Cancer Center
🇺🇸Honolulu, Hawaii, United States
University of California Davis Comprehensive Cancer Center
🇺🇸Sacramento, California, United States
AdventHealth Orlando
🇺🇸Orlando, Florida, United States
Nemours Children's Clinic - Orlando
🇺🇸Orlando, Florida, United States
UF Cancer Center at Orlando Health
🇺🇸Orlando, Florida, United States
Nemours Children's Hospital
🇺🇸Orlando, Florida, United States
Norton Children's Hospital
🇺🇸Louisville, Kentucky, United States
C S Mott Children's Hospital
🇺🇸Ann Arbor, Michigan, United States
Wake Forest University Health Sciences
🇺🇸Winston-Salem, North Carolina, United States
Kalamazoo Center for Medical Studies
🇺🇸Kalamazoo, Michigan, United States
IWK Health Centre
🇨🇦Halifax, Nova Scotia, Canada
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
🇺🇸New Brunswick, New Jersey, United States
Penn State Children's Hospital
🇺🇸Hershey, Pennsylvania, United States
University of Chicago Comprehensive Cancer Center
🇺🇸Chicago, Illinois, United States
University of Rochester
🇺🇸Rochester, New York, United States
Mount Sinai Hospital
🇺🇸New York, New York, United States
Dartmouth Hitchcock Medical Center
🇺🇸Lebanon, New Hampshire, United States
University of Mississippi Medical Center
🇺🇸Jackson, Mississippi, United States
State University of New York Upstate Medical University
🇺🇸Syracuse, New York, United States
Mission Hospital Inc-Memorial Campus
🇺🇸Asheville, North Carolina, United States
University of Arkansas for Medical Sciences
🇺🇸Little Rock, Arkansas, United States
Kaiser Permanente-Oakland
🇺🇸Oakland, California, United States
Kaiser Permanente Downey Medical Center
🇺🇸Downey, California, United States
Children's National Medical Center
🇺🇸Washington, District of Columbia, United States
Phoenix Childrens Hospital
🇺🇸Phoenix, Arizona, United States
Children's Hospital of Alabama
🇺🇸Birmingham, Alabama, United States
Alfred I duPont Hospital for Children
🇺🇸Wilmington, Delaware, United States
Advocate Children's Hospital-Oak Lawn
🇺🇸Oak Lawn, Illinois, United States
UMass Memorial Medical Center - University Campus
🇺🇸Worcester, Massachusetts, United States
Broward Health Medical Center
🇺🇸Fort Lauderdale, Florida, United States
Memorial Health University Medical Center
🇺🇸Savannah, Georgia, United States
Loyola University Medical Center
🇺🇸Maywood, Illinois, United States
Nemours Children's Clinic-Jacksonville
🇺🇸Jacksonville, Florida, United States
Children's Hospital of Orange County
🇺🇸Orange, California, United States
Southern Illinois University School of Medicine
🇺🇸Springfield, Illinois, United States
Baystate Medical Center
🇺🇸Springfield, Massachusetts, United States
Golisano Children's Hospital of Southwest Florida
🇺🇸Fort Myers, Florida, United States
Johns Hopkins All Children's Hospital
🇺🇸Saint Petersburg, Florida, United States
New York Medical College
🇺🇸Valhalla, New York, United States
Memorial Sloan Kettering Cancer Center
🇺🇸New York, New York, United States
Hackensack University Medical Center
🇺🇸Hackensack, New Jersey, United States
Loma Linda University Medical Center
🇺🇸Loma Linda, California, United States
University of New Mexico Cancer Center
🇺🇸Albuquerque, New Mexico, United States
Arkansas Children's Hospital
🇺🇸Little Rock, Arkansas, United States
Lucile Packard Children's Hospital Stanford University
🇺🇸Palo Alto, California, United States
Helen DeVos Children's Hospital at Spectrum Health
🇺🇸Grand Rapids, Michigan, United States
MedStar Georgetown University Hospital
🇺🇸Washington, District of Columbia, United States
Sinai Hospital of Baltimore
🇺🇸Baltimore, Maryland, United States
Children's Healthcare of Atlanta - Egleston
🇺🇸Atlanta, Georgia, United States
Saint Jude Midwest Affiliate
🇺🇸Peoria, Illinois, United States
Columbia Regional
🇺🇸Columbia, Missouri, United States
University of Kansas Cancer Center
🇺🇸Kansas City, Kansas, United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
🇺🇸Hollywood, Florida, United States
Saint Mary's Hospital
🇺🇸West Palm Beach, Florida, United States
Bronson Methodist Hospital
🇺🇸Kalamazoo, Michigan, United States
Nemours Children's Clinic - Pensacola
🇺🇸Pensacola, Florida, United States
Michigan State University Clinical Center
🇺🇸East Lansing, Michigan, United States
Cardinal Glennon Children's Medical Center
🇺🇸Saint Louis, Missouri, United States
Washington University School of Medicine
🇺🇸Saint Louis, Missouri, United States
Mercy Hospital Saint Louis
🇺🇸Saint Louis, Missouri, United States
UT Southwestern/Simmons Cancer Center-Dallas
🇺🇸Dallas, Texas, United States
Marshfield Medical Center-Marshfield
🇺🇸Marshfield, Wisconsin, United States
University of Kentucky/Markey Cancer Center
🇺🇸Lexington, Kentucky, United States
Dayton Children's Hospital
🇺🇸Dayton, Ohio, United States
University of Iowa/Holden Comprehensive Cancer Center
🇺🇸Iowa City, Iowa, United States
Madigan Army Medical Center
🇺🇸Tacoma, Washington, United States
University of Vermont and State Agricultural College
🇺🇸Burlington, Vermont, United States
Saint Luke's Mountain States Tumor Institute
🇺🇸Boise, Idaho, United States
Geisinger Medical Center
🇺🇸Danville, Pennsylvania, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
🇺🇸New York, New York, United States
Royal Brisbane and Women's Hospital
🇦🇺Herston, Queensland, Australia
Hurley Medical Center
🇺🇸Flint, Michigan, United States
T C Thompson Children's Hospital
🇺🇸Chattanooga, Tennessee, United States
Summerlin Hospital Medical Center
🇺🇸Las Vegas, Nevada, United States
Novant Health Presbyterian Medical Center
🇺🇸Charlotte, North Carolina, United States
Roswell Park Cancer Institute
🇺🇸Buffalo, New York, United States
Greenville Cancer Treatment Center
🇺🇸Greenville, South Carolina, United States
Morristown Medical Center
🇺🇸Morristown, New Jersey, United States
The Steven and Alexandra Cohen Children's Medical Center of New York
🇺🇸New Hyde Park, New York, United States
Driscoll Children's Hospital
🇺🇸Corpus Christi, Texas, United States
Centre Hospitalier Universitaire de Quebec
🇨🇦Quebec, Canada
Cook Children's Medical Center
🇺🇸Fort Worth, Texas, United States
Albany Medical Center
🇺🇸Albany, New York, United States
Saint Vincent Hospital Cancer Center Green Bay
🇺🇸Green Bay, Wisconsin, United States
Stony Brook University Medical Center
🇺🇸Stony Brook, New York, United States
Children's Hospital Medical Center of Akron
🇺🇸Akron, Ohio, United States
Prisma Health Richland Hospital
🇺🇸Columbia, South Carolina, United States
Carolinas Medical Center/Levine Cancer Institute
🇺🇸Charlotte, North Carolina, United States
Sanford USD Medical Center - Sioux Falls
🇺🇸Sioux Falls, South Dakota, United States
Children's Hospital of The King's Daughters
🇺🇸Norfolk, Virginia, United States
Providence Sacred Heart Medical Center and Children's Hospital
🇺🇸Spokane, Washington, United States
Saskatoon Cancer Centre
🇨🇦Saskatoon, Saskatchewan, Canada
Saint Joseph's Regional Medical Center
🇺🇸Paterson, New Jersey, United States
Overlook Hospital
🇺🇸Summit, New Jersey, United States
Brooke Army Medical Center
🇺🇸Fort Sam Houston, Texas, United States
University Pediatric Hospital
🇵🇷San Juan, Puerto Rico
Royal Children's Hospital-Brisbane
🇦🇺Herston, Queensland, Australia
BI-LO Charities Children's Cancer Center
🇺🇸Greenville, South Carolina, United States
Queensland Children's Hospital
🇦🇺South Brisbane, Queensland, Australia
East Tennessee Childrens Hospital
🇺🇸Knoxville, Tennessee, United States
Mercy Children's Hospital
🇺🇸Toledo, Ohio, United States
Lehigh Valley Hospital - Muhlenberg
🇺🇸Bethlehem, Pennsylvania, United States
McMaster Children's Hospital at Hamilton Health Sciences
🇨🇦Hamilton, Ontario, Canada
Women's and Children's Hospital-Adelaide
🇦🇺North Adelaide, South Australia, Australia
Medical City Dallas Hospital
🇺🇸Dallas, Texas, United States
The Montreal Children's Hospital of the MUHC
🇨🇦Montreal, Quebec, Canada
San Jorge Children's Hospital
🇵🇷San Juan, Puerto Rico
Children's Hospital of Eastern Ontario
🇨🇦Ottawa, Ontario, Canada
Carilion Clinic Children's Hospital
🇺🇸Roanoke, Virginia, United States
Children's Hospital of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States
Swiss Pediatric Oncology Group - Bern
🇨🇭Bern, Switzerland
British Columbia Children's Hospital
🇨🇦Vancouver, British Columbia, Canada
Princess Margaret Hospital for Children
🇦🇺Perth, Western Australia, Australia
Centre Hospitalier Universitaire Sainte-Justine
🇨🇦Montreal, Quebec, Canada
Starship Children's Hospital
🇳🇿Grafton, Auckland, New Zealand
Alberta Children's Hospital
🇨🇦Calgary, Alberta, Canada
University of Alberta Hospital
🇨🇦Edmonton, Alberta, Canada
Children's Mercy Hospitals and Clinics
🇺🇸Kansas City, Missouri, United States
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States
Kapiolani Medical Center for Women and Children
🇺🇸Honolulu, Hawaii, United States
Ochsner Medical Center Jefferson
🇺🇸New Orleans, Louisiana, United States
Tulane University Health Sciences Center
🇺🇸New Orleans, Louisiana, United States
Montefiore Medical Center - Moses Campus
🇺🇸Bronx, New York, United States
Dell Children's Medical Center of Central Texas
🇺🇸Austin, Texas, United States
Rhode Island Hospital
🇺🇸Providence, Rhode Island, United States