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Clinical Study of Stent Versus Direct Atherectomy to Treat Arteriosclerosis Occlusive Disease of Lower Extremity

Not Applicable
Completed
Conditions
Ischemia
Atherosclerosis
Interventions
Device: balloon and Stent
Device: plaque excision system
Registration Number
NCT02840786
Lead Sponsor
Xuanwu Hospital, Beijing
Brief Summary

This is a randomized study comparing stent and plaque excision systems in treatment of Arteriosclerosis occlusive disease of lower extremity (superficial femoral or popliteal artery)

Detailed Description

This is a randomized study comparing balloon angioplasty adjunctive stent and plaque excision systems in treatment of Arteriosclerosis occlusive disease of lower extremity (superficial femoral or popliteal artery)

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
221
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Intervention: Stentsballoon and StentStents group
Intervention: Atherectomyplaque excision systemdirectional atherectomy group
Primary Outcome Measures
NameTimeMethod
12-month Primary Patency Rate12 months

systolic velocity ratio \>2.4 as measured by Duplex ultrasound.

Secondary Outcome Measures
NameTimeMethod
Technical success1 day

Technical success was defined as residual stenosis less than 30% by final angiography and/or a flow-limiting dissection.

freedom from clinically-driven TLR12 months

it is defined as thefreedom from clinically-driven target lesion revascularization

Major Adverse Events at 12-month Post Procedure12 months

Major adverse events included death, index limb ischemia, index limb amputation, clinically driven target lesion revascularization , and significant embolic events, which were defined as causing end-organ damage.

12-month Limb Salvage Rate12 months

Limb Salvage is defined as the freedom from secondary major amputation

Trial Locations

Locations (1)

Gu Yong Quan

🇨🇳

Beijing, Beijing, China

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