Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients

Phase 3

Completed

Conditions: Diabetes Mellitus, Type 2

Interventions: Drug: high dose FDC
Drug: low dose FDC placebo
Drug: BI 10773 high dose
Drug: high dose FDC placebo
Drug: low dose FDC
Drug: high dose BI 10773 placebo
Drug: linagliptin
Drug: low dose BI 10773 placebo
Drug: BI 10773 low dose placebo
Drug: BI 10773 low dose
Drug: linagliptin placebo

Registration Number: NCT01422876

Lead Sponsor: Boehringer Ingelheim

Brief Summary: This trial will evaluate use of BI 10773/linagliptin once daily (qd) fixed dose combination (FDC) in treatment naïve and metformin treated patients with type 2 diabetes mellitus to support approval by regulatory authorities.

Detailed Description: Not available

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 1405

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
BI 10773/linagliptin FDC (high dose)	linagliptin placebo	Patients receive BI 10773/linagliptin FDC (high dose) once daily
BI 10773 (high dose)	linagliptin placebo	Patients receive BI 10773 (high dose) once daily
BI 10773 (low dose)	linagliptin placebo	Patients receive BI 10773 (low dose) once daily
BI 10773/linagliptin FDC (high dose)	high dose FDC	Patients receive BI 10773/linagliptin FDC (high dose) once daily
BI 10773/linagliptin FDC (high dose)	high dose BI 10773 placebo	Patients receive BI 10773/linagliptin FDC (high dose) once daily
BI 10773 (low dose)	high dose BI 10773 placebo	Patients receive BI 10773 (low dose) once daily
Linagliptin	high dose BI 10773 placebo	Patients receive linagliptin once daily
BI 10773/linagliptin FDC (low dose)	linagliptin placebo	Patients receive BI 10773/linagliptin FDC (low dose) once daily
BI 10773 (high dose)	high dose FDC placebo	Patients receive BI 10773 (high dose) once daily
Linagliptin	high dose FDC placebo	Patients receive linagliptin once daily
Linagliptin	linagliptin	Patients receive linagliptin once daily
BI 10773/linagliptin FDC (low dose)	high dose FDC placebo	Patients receive BI 10773/linagliptin FDC (low dose) once daily
BI 10773/linagliptin FDC (low dose)	high dose BI 10773 placebo	Patients receive BI 10773/linagliptin FDC (low dose) once daily
Linagliptin	low dose FDC placebo	Patients receive linagliptin once daily
BI 10773/linagliptin FDC (high dose)	low dose FDC placebo	Patients receive BI 10773/linagliptin FDC (high dose) once daily
BI 10773 (high dose)	low dose BI 10773 placebo	Patients receive BI 10773 (high dose) once daily
BI 10773/linagliptin FDC (high dose)	BI 10773 low dose placebo	Patients receive BI 10773/linagliptin FDC (high dose) once daily
BI 10773/linagliptin FDC (low dose)	low dose FDC	Patients receive BI 10773/linagliptin FDC (low dose) once daily
BI 10773/linagliptin FDC (low dose)	BI 10773 low dose placebo	Patients receive BI 10773/linagliptin FDC (low dose) once daily
BI 10773 (high dose)	BI 10773 high dose	Patients receive BI 10773 (high dose) once daily
BI 10773 (low dose)	high dose FDC placebo	Patients receive BI 10773 (low dose) once daily
BI 10773 (low dose)	BI 10773 low dose	Patients receive BI 10773 (low dose) once daily
Linagliptin	low dose BI 10773 placebo	Patients receive linagliptin once daily
BI 10773 (high dose)	low dose FDC placebo	Patients receive BI 10773 (high dose) once daily
BI 10773 (low dose)	low dose FDC placebo	Patients receive BI 10773 (low dose) once daily

Primary Outcome Measures

Name	Time	Method
Change From Baseline in Glycosylated Hemoglobin (HbA1c) for Treatment Naive Patients	Baseline and 24 weeks	Glycosylated hemoglobin (HbA1c) is a measurement of the percentage of hemoglobin that is glycated. The change from baseline in HbA1c is calculated as the week 24 HbA1c minus the baseline HbA1c. Since HbA1c is measured as a percentage the change from baseline is also a percentage.
Change From Baseline in Glycosylated Hemoglobin (HbA1c) for Metformin Background Patients	Baseline and 24 weeks	Glycosylated hemoglobin (HbA1c) is a measurement of the percentage of hemoglobin that is glycated. The change from baseline in HbA1c is calculated as the week 24 HbA1c minus the baseline HbA1c. Since HbA1c is measured as a percentage the change from baseline is also a percentage.

Secondary Outcome Measures

Name	Time	Method
Change From Baseline in Body Weight for Metformin Background Patients	Baseline and 24 Weeks	Change from baseline in body weight for Metformin Background patients.
Change From Baseline in Fasting Plasma Glucose at Week 24 for Treatment Naive Patients	Baseline and 24 Weeks	Change from baseline in fasting plasma glucose at week 24 for Treatment Naive patients.
Change From Baseline in Fasting Plasma Glucose at Week 24 for Metformin Background Patients	Baseline and 24 Weeks	Change from baseline in fasting plasma glucose at week 24 for Metformin Background patients.
Change From Baseline in Body Weight for Treatment Naive Patients	Baseline and 24 Weeks	Change from baseline in body weight for Treatment Naive patients.
Occurrence of Treat to Target Efficacy Response for Metformin Background Patients	24 Weeks	Occurrence of the treat-to-target efficacy response for Metformin Background patients measured as HbA1c \< 7.0% after 24 weeks of treatment for patients with HbA1c \>=7.0% at baseline.
Occurrence of Treat to Target Efficacy Response for Treatment Naive Patients	24 Weeks	Occurrence of the treat-to-target efficacy response for Treatment Naive patients measured as HbA1c \< 7.0% after 24 weeks of treatment for patients with HbA1c \>=7.0% at baseline.

Trial Locations

Locations (211): 1275.1.01043 Boehringer Ingelheim Investigational Site
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Mobile, Alabama, United States
1275.1.01039 Boehringer Ingelheim Investigational Site
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Atlanta, Georgia, United States
1275.1.01003 Boehringer Ingelheim Investigational Site
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Shreveport, Louisiana, United States
1275.1.01001 Boehringer Ingelheim Investigational Site
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Akron, Ohio, United States
1275.1.01022 Boehringer Ingelheim Investigational Site
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West Jordan, Utah, United States
1275.1.20001 Boehringer Ingelheim Investigational Site
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Brampton, Ontario, Canada
1275.1.20005 Boehringer Ingelheim Investigational Site
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Toronto, Ontario, Canada
1275.1.01016 Boehringer Ingelheim Investigational Site
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Columbus, Ohio, United States
1275.1.01102 Boehringer Ingelheim Investigational Site
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Columbus, Ohio, United States
1275.1.01034 Boehringer Ingelheim Investigational Site
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Norman, Oklahoma, United States
1275.1.01019 Boehringer Ingelheim Investigational Site
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Pittsburgh, Pennsylvania, United States
1275.1.01081 Boehringer Ingelheim Investigational Site
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Boston, Massachusetts, United States
1275.1.01053 Boehringer Ingelheim Investigational Site
🇺🇸
Houston, Texas, United States
1275.1.01106 Boehringer Ingelheim Investigational Site
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Houston, Texas, United States
1275.1.20002 Boehringer Ingelheim Investigational Site
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Pointe Claire, Quebec, Canada
1275.1.52001 Boehringer Ingelheim Investigational Site
🇲🇽
Pachuca, Mexico
1275.1.01101 Boehringer Ingelheim Investigational Site
🇺🇸
Las Vegas, Nevada, United States
1275.1.01123 Boehringer Ingelheim Investigational Site
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Las Vegas, Nevada, United States
1275.1.60002 Boehringer Ingelheim Investigational Site
🇲🇾
Perak, Malaysia
1275.1.96007 Boehringer Ingelheim Investigational Site
🇱🇧
Saida, Lebanon
1275.1.01032 Boehringer Ingelheim Investigational Site
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Cincinnati, Ohio, United States
1275.1.01061 Boehringer Ingelheim Investigational Site
🇺🇸
Cincinnati, Ohio, United States
1275.1.01116 Boehringer Ingelheim Investigational Site
🇺🇸
Cincinnati, Ohio, United States
1275.1.01096 Boehringer Ingelheim Investigational Site
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San Antonio, Texas, United States
1275.1.01113 Boehringer Ingelheim Investigational Site
🇺🇸
San Antonio, Texas, United States
1275.1.01120 Boehringer Ingelheim Investigational Site
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San Antonio, Texas, United States
1275.1.01028 Boehringer Ingelheim Investigational Site
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Little Rock, Arkansas, United States
1275.1.54004 Boehringer Ingelheim Investigational Site
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Mar del Plata, Argentina
1275.1.01099 Boehringer Ingelheim Investigational Site
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Henderson, Nevada, United States
1275.1.01064 Boehringer Ingelheim Investigational Site
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Tempe, Arizona, United States
1275.1.01005 Boehringer Ingelheim Investigational Site
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Hodges, South Carolina, United States
1275.1.96003 Boehringer Ingelheim Investigational Site
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Beirut, Lebanon
1275.1.96006 Boehringer Ingelheim Investigational Site
🇱🇧
Beirut, Lebanon
1275.1.01114 Boehringer Ingelheim Investigational Site
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Las Vegas, Nevada, United States
1275.1.51002 Boehringer Ingelheim Investigational Site
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Lima, Peru
1275.1.57005 Boehringer Ingelheim Investigational Site
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Bogota, Colombia
1275.1.57002 Boehringer Ingelheim Investigational Site
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Bogotá, Colombia
1275.1.52003 Boehringer Ingelheim Investigational Site
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Monterrey, Mexico
1275.1.51003 Boehringer Ingelheim Investigational Site
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Ica, Peru
1275.1.51005 Boehringer Ingelheim Investigational Site
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Lima, Peru
1275.1.63002 Boehringer Ingelheim Investigational Site
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Davao, Philippines
1275.1.48002 Boehringer Ingelheim Investigational Site
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Lodz, Poland
1275.1.01015 Boehringer Ingelheim Investigational Site
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Brentwood, Tennessee, United States
1275.1.57004 Boehringer Ingelheim Investigational Site
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Barranquilla, Colombia
1275.1.37201 Boehringer Ingelheim Investigational Site
🇪🇪
Tallinn, Estonia
1275.1.57003 Boehringer Ingelheim Investigational Site
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Tolima, Colombia
1275.1.51004 Boehringer Ingelheim Investigational Site
🇵🇪
Lima, Peru
1275.1.63003 Boehringer Ingelheim Investigational Site
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Pasay City, Philippines
1275.1.48004 Boehringer Ingelheim Investigational Site
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Poznan, Poland
1275.1.40008 Boehringer Ingelheim Investigational Site
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Bucharest, Romania
1275.1.37202 Boehringer Ingelheim Investigational Site
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Pärnu, Estonia
1275.1.36001 Boehringer Ingelheim Investigational Site
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Gyongyos, Hungary
1275.1.96008 Boehringer Ingelheim Investigational Site
🇱🇧
Beirut, Lebanon
1275.1.60001 Boehringer Ingelheim Investigational Site
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Kedah, Malaysia
1275.1.52002 Boehringer Ingelheim Investigational Site
🇲🇽
Mexico, Mexico
1275.1.48003 Boehringer Ingelheim Investigational Site
🇵🇱
Warsaw, Poland
1275.1.70006 Boehringer Ingelheim Investigational Site
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Arkhangelsk, Russian Federation
1275.1.88001 Cardinal Tien Hospital
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New Taipei, Taiwan
1275.1.63004 Boehringer Ingelheim Investigational Site
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Manila, Philippines
1275.1.63005 Boehringer Ingelheim Investigational Site
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Pasig, Philippines
1275.1.40004 Boehringer Ingelheim Investigational Site
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Brasov, Romania
1275.1.70005 Boehringer Ingelheim Investigational Site
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St. Petersburg, Russian Federation
1275.1.40001 Boehringer Ingelheim Investigational Site
🇷🇴
Alba Iulia, Romania
1275.1.40010 Boehringer Ingelheim Investigational Site
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Sibiu, Romania
1275.1.70004 Boehringer Ingelheim Investigational Site
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Samara, Russian Federation
1275.1.88004 Taichung Veterans General Hospital
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Taichung, Taiwan
1275.1.88008 Chi Mei Medical Center
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Tainan, Taiwan
1275.1.88003 Taipei Chang Gung Memorial Hospital
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Taipei, Taiwan
1275.1.88006 Chang Gung Memorial Hospital-CY
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Chiayi, Taiwan
1275.1.88007 E-Da Hospital
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Kaohsiung, Taiwan
1275.1.70001 Boehringer Ingelheim Investigational Site
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Moscow, Russian Federation
1275.1.01103 Boehringer Ingelheim Investigational Site
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Birmingham, Alabama, United States
1275.1.01048 Boehringer Ingelheim Investigational Site
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Denver, Colorado, United States
1275.1.01107 Boehringer Ingelheim Investigational Site
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Foley, Alabama, United States
1275.1.01066 Boehringer Ingelheim Investigational Site
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Mobile, Alabama, United States
1275.1.01047 Boehringer Ingelheim Investigational Site
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Pell City, Alabama, United States
1275.1.01089 Boehringer Ingelheim Investigational Site
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Mesa, Arizona, United States
1275.1.01086 Boehringer Ingelheim Investigational Site
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Cerritos, California, United States
1275.1.01067 Boehringer Ingelheim Investigational Site
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Chula Vista, California, United States
1275.1.01012 Boehringer Ingelheim Investigational Site
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Fresno, California, United States
1275.1.01109 Boehringer Ingelheim Investigational Site
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Encino, California, United States
1275.1.01050 Boehringer Ingelheim Investigational Site
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Harbor City, California, United States
1275.1.01056 Boehringer Ingelheim Investigational Site
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Huntington Park, California, United States
1275.1.01021 Boehringer Ingelheim Investigational Site
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Long Beach, California, United States
1275.1.01024 Boehringer Ingelheim Investigational Site
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Los Angeles, California, United States
1275.1.01112 Boehringer Ingelheim Investigational Site
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Los Angeles, California, United States
1275.1.01083 Boehringer Ingelheim Investigational Site
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Oceanside, California, United States
1275.1.01071 Boehringer Ingelheim Investigational Site
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San Dimas, California, United States
1275.1.01078 Boehringer Ingelheim Investigational Site
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Colorado Springs, Colorado, United States
1275.1.01044 Boehringer Ingelheim Investigational Site
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Tustin, California, United States
1275.1.01124 Boehringer Ingelheim Investigational Site
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Colorado Springs, Colorado, United States
1275.1.01010 Boehringer Ingelheim Investigational Site
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Denver, Colorado, United States
1275.1.01063 Boehringer Ingelheim Investigational Site
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Hialeah, Florida, United States
1275.1.01077 Boehringer Ingelheim Investigational Site
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Hialeah, Florida, United States
1275.1.01092 Boehringer Ingelheim Investigational Site
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Maitland, Florida, United States
1275.1.01054 Boehringer Ingelheim Investigational Site
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Jacksonville, Florida, United States
1275.1.01090 Boehringer Ingelheim Investigational Site
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Inverness, Florida, United States
1275.1.01025 Boehringer Ingelheim Investigational Site
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Miami Lakes, Florida, United States
1275.1.01065 Boehringer Ingelheim Investigational Site
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Miami, Florida, United States
1275.1.01040 Boehringer Ingelheim Investigational Site
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Miami Beach, Florida, United States
1275.1.01110 Boehringer Ingelheim Investigational Site
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Miami, Florida, United States
1275.1.01068 Boehringer Ingelheim Investigational Site
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Ormond Beach, Florida, United States
1275.1.01051 Boehringer Ingelheim Investigational Site
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Pembroke Pines, Florida, United States
1275.1.01079 Boehringer Ingelheim Investigational Site
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Port Orange, Florida, United States
1275.1.01117 Boehringer Ingelheim Investigational Site
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St. Petersburg, Florida, United States
1275.1.01111 Boehringer Ingelheim Investigational Site
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Norcross, Georgia, United States
1275.1.01100 Boehringer Ingelheim Investigational Site
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Addison, Illinois, United States
1275.1.01007 Boehringer Ingelheim Investigational Site
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Marietta, Georgia, United States
1275.1.01076 Boehringer Ingelheim Investigational Site
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Savannah, Georgia, United States
1275.1.01059 Boehringer Ingelheim Investigational Site
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Paducah, Kentucky, United States
1275.1.01125 Boehringer Ingelheim Investigational Site
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Hyattsville, Maryland, United States
1275.1.01035 Boehringer Ingelheim Investigational Site
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Southfield, Michigan, United States
1275.1.01085 Boehringer Ingelheim Investigational Site
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Rochester, Michigan, United States
1275.1.01027 Boehringer Ingelheim Investigational Site
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St. Louis, Missouri, United States
1275.1.01023 Boehringer Ingelheim Investigational Site
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St. Louis, Missouri, United States
1275.1.01033 Boehringer Ingelheim Investigational Site
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Great Falls, Montana, United States
1275.1.01013 Boehringer Ingelheim Investigational Site
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Elizabeth, New Jersey, United States
1275.1.01002 Boehringer Ingelheim Investigational Site
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Binghamton, New York, United States
1275.1.01020 Boehringer Ingelheim Investigational Site
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Endwell, New York, United States
1275.1.01095 Boehringer Ingelheim Investigational Site
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Flushing, New York, United States
1275.1.01006 Boehringer Ingelheim Investigational Site
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New York, New York, United States
1275.1.01062 Boehringer Ingelheim Investigational Site
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Glens Falls, New York, United States
1275.1.01011 Boehringer Ingelheim Investigational Site
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Asheboro, North Carolina, United States
1275.1.01045 Boehringer Ingelheim Investigational Site
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Charlotte, North Carolina, United States
1275.1.01052 Boehringer Ingelheim Investigational Site
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Burlington, North Carolina, United States
1275.1.01030 Boehringer Ingelheim Investigational Site
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Delaware, Ohio, United States
1275.1.01075 Boehringer Ingelheim Investigational Site
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Wadsworth, Ohio, United States
1275.1.01055 Boehringer Ingelheim Investigational Site
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Groveport, Ohio, United States
1275.1.01084 Boehringer Ingelheim Investigational Site
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Altoona, Pennsylvania, United States
1275.1.01082 Boehringer Ingelheim Investigational Site
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Corvallis, Oregon, United States
1275.1.01038 Boehringer Ingelheim Investigational Site
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Fleetwood, Pennsylvania, United States
1275.1.01072 Boehringer Ingelheim Investigational Site
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Scottdale, Pennsylvania, United States
1275.1.01088 Boehringer Ingelheim Investigational Site
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Tipton, Pennsylvania, United States
1275.1.01060 Boehringer Ingelheim Investigational Site
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Uniontown, Pennsylvania, United States
1275.1.01031 Boehringer Ingelheim Investigational Site
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Chattanooga, Tennessee, United States
1275.1.01122 Boehringer Ingelheim Investigational Site
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Florence, South Carolina, United States
1275.1.01069 Boehringer Ingelheim Investigational Site
🇺🇸
Spring Hill, Tennessee, United States
1275.1.01121 Boehringer Ingelheim Investigational Site
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Memphis, Tennessee, United States
1275.1.01029 Boehringer Ingelheim Investigational Site
🇺🇸
Houston, Texas, United States
1275.1.01037 Boehringer Ingelheim Investigational Site
🇺🇸
Waco, Texas, United States
1275.1.01018 Boehringer Ingelheim Investigational Site
🇺🇸
Pearland, Texas, United States
1275.1.01105 Boehringer Ingelheim Investigational Site
🇺🇸
Spring, Texas, United States
1275.1.01008 Boehringer Ingelheim Investigational Site
🇺🇸
Bountiful, Utah, United States
1275.1.01118 Boehringer Ingelheim Investigational Site
🇺🇸
Selah, Washington, United States
1275.1.01087 Boehringer Ingelheim Investigational Site
🇺🇸
Shoreline, Washington, United States
1275.1.01091 Boehringer Ingelheim Investigational Site
🇺🇸
South Chesterfield, Virginia, United States
1275.1.01119 Boehringer Ingelheim Investigational Site
🇺🇸
Spokane, Washington, United States
1275.1.54005 Boehringer Ingelheim Investigational Site
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Capital Federal, Argentina
1275.1.54001 Boehringer Ingelheim Investigational Site
🇦🇷
Caba, Argentina
1275.1.54003 Boehringer Ingelheim Investigational Site
🇦🇷
Cordoba, Argentina
1275.1.61003 Boehringer Ingelheim Investigational Site
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Wollongong, New South Wales, Australia
1275.1.54002 Boehringer Ingelheim Investigational Site
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Mendoza, Argentina
1275.1.61002 Boehringer Ingelheim Investigational Site
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East Ringwood, Victoria, Australia
1275.1.55002 Boehringer Ingelheim Investigational Site
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Joaquim Távora, Brazil
1275.1.55001 Boehringer Ingelheim Investigational Site
🇧🇷
Rio de Janeiro - RJ, Brazil
1275.1.59003 Boehringer Ingelheim Investigational Site
🇧🇬
Plovdiv, Bulgaria
1275.1.55005 Boehringer Ingelheim Investigational Site
🇧🇷
Sao Paulo, Brazil
1275.1.59006 Boehringer Ingelheim Investigational Site
🇧🇬
Ruse, Bulgaria
1275.1.20008 Boehringer Ingelheim Investigational Site
🇨🇦
Bathurst, New Brunswick, Canada
1275.1.59004 Boehringer Ingelheim Investigational Site
🇧🇬
Sofia, Bulgaria
1275.1.20004 Boehringer Ingelheim Investigational Site
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St. John's, Newfoundland and Labrador, Canada
1275.1.20006 Boehringer Ingelheim Investigational Site
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Mount Pearl, Newfoundland and Labrador, Canada
1275.1.20007 Boehringer Ingelheim Investigational Site
🇨🇦
Bay Roberts, Newfoundland and Labrador, Canada
1275.1.20003 Boehringer Ingelheim Investigational Site
🇨🇦
Drummondville, Quebec, Canada
1275.1.45004 Boehringer Ingelheim Investigational Site
🇩🇰
Aalborg, Denmark
1275.1.37206 Boehringer Ingelheim Investigational Site
🇪🇪
Kivioli, Estonia
1275.1.45003 Boehringer Ingelheim Investigational Site
🇩🇰
Aarhus C, Denmark
1275.1.45002 Boehringer Ingelheim Investigational Site
🇩🇰
København NV, Denmark
1275.1.37204 Boehringer Ingelheim Investigational Site
🇪🇪
Tallinn, Estonia
1275.1.37203 Boehringer Ingelheim Investigational Site
🇪🇪
Viljandi County, Estonia
1275.1.36002 Boehringer Ingelheim Investigational Site
🇭🇺
Budapest, Hungary
1275.1.36003 Boehringer Ingelheim Investigational Site
🇭🇺
Budapest, Hungary
1275.1.39001 Boehringer Ingelheim Investigational Site
🇮🇹
Milan, Italy
1275.1.39003 Boehringer Ingelheim Investigational Site
🇮🇹
Bassano del Grappa (VI), Italy
1275.1.39002 Boehringer Ingelheim Investigational Site
🇮🇹
Fermo, Italy
1275.1.39004 Boehringer Ingelheim Investigational Site
🇮🇹
Roma, Italy
1275.1.96004 Boehringer Ingelheim Investigational Site
🇱🇧
Baabda, Lebanon
1275.1.96002 Boehringer Ingelheim Investigational Site
🇱🇧
Beirut, Lebanon
1275.1.52005 Boehringer Ingelheim Investigational Site
🇲🇽
Mexico, Mexico
1275.1.52004 Boehringer Ingelheim Investigational Site
🇲🇽
San Luis Potosí, Mexico
1275.1.63001 Boehringer Ingelheim Investigational Site
🇵🇭
Greenhills, San Juan, Philippines
1275.1.51001 Boehringer Ingelheim Investigational Site
🇵🇪
Arequipa, Peru
1275.1.63006 Boehringer Ingelheim Investigational Site
🇵🇭
Marikina city, Philippines
1275.1.48001 Boehringer Ingelheim Investigational Site
🇵🇱
Warsaw, Poland
1275.1.40009 Boehringer Ingelheim Investigational Site
🇷🇴
Bucharest, Romania
1275.1.40005 Boehringer Ingelheim Investigational Site
🇷🇴
Baia Mare Maramures, Romania
1275.1.40006 Boehringer Ingelheim Investigational Site
🇷🇴
Cluj-Napoca, Romania
1275.1.40007 Boehringer Ingelheim Investigational Site
🇷🇴
Galati, Romania
1275.1.40002 Boehringer Ingelheim Investigational Site
🇷🇴
Oradea, Romania
1275.1.40003 Boehringer Ingelheim Investigational Site
🇷🇴
Targu-Mures, Romania
1275.1.70002 Boehringer Ingelheim Investigational Site
🇷🇺
St. Petersburg, Russian Federation
1275.1.34003 Boehringer Ingelheim Investigational Site
🇪🇸
Palma de Mallorca, Spain
1275.1.34002 Boehringer Ingelheim Investigational Site
🇪🇸
Hospitalet de Llobegrat, Spain
1275.1.34005 Boehringer Ingelheim Investigational Site
🇪🇸
Barcelona, Spain
1275.1.70003 Boehringer Ingelheim Investigational Site
🇷🇺
St. Petersburg, Russian Federation
1275.1.46003 Boehringer Ingelheim Investigational Site
🇸🇪
Järfälla, Sweden
1275.1.34004 Boehringer Ingelheim Investigational Site
🇪🇸
Barcelona, Spain
1275.1.34006 Boehringer Ingelheim Investigational Site
🇪🇸
Tarragona, Spain
1275.1.46004 Boehringer Ingelheim Investigational Site
🇸🇪
Rättvik, Sweden
1275.1.46002 Boehringer Ingelheim Investigational Site
🇸🇪
Skene, Sweden
1275.1.88002 Far Eastern Memorial Hospital
🇨🇳
Taipei, Taiwan
1275.1.01073 Boehringer Ingelheim Investigational Site
🇺🇸
Gainesville, Florida, United States
1275.1.01094 Boehringer Ingelheim Investigational Site
🇺🇸
Orlando, Florida, United States
1275.1.01042 Boehringer Ingelheim Investigational Site
🇺🇸
Des Moines, Iowa, United States
1275.1.01057 Boehringer Ingelheim Investigational Site
🇺🇸
Albuquerque, New Mexico, United States
1275.1.01093 Boehringer Ingelheim Investigational Site
🇺🇸
Charleston, South Carolina, United States
1275.1.01049 Boehringer Ingelheim Investigational Site
🇺🇸
Austin, Texas, United States
1275.1.01080 Boehringer Ingelheim Investigational Site
🇺🇸
Austin, Texas, United States
1275.1.01017 Boehringer Ingelheim Investigational Site
🇺🇸
Dayton, Ohio, United States
1275.1.01036 Boehringer Ingelheim Investigational Site
🇺🇸
Dayton, Ohio, United States
1275.1.01014 Boehringer Ingelheim Investigational Site
🇺🇸
Uniontown, Pennsylvania, United States