Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes Among Infective Endocaridtis Patients in a Tertiary-care Centre in Kerala
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infective Endocarditis
- Sponsor
- Government Medical College, Kozhikode
- Enrollment
- 102
- Primary Endpoint
- Major complications
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The investigators conduct a prospective observational study on consecutive patients being admitted to a tertiary care-centre with infective endocarditis. The investigators' primary aim is to identify baseline clincal, laboratory and microbiological predictors of in-hospital events, mortality and 6-month mortality.
Detailed Description
Mortality and major complications among infective endocarditis remain high. In addition developing nations are crippled with a high incidence of culture-negative endocarditis and lack of wide availability of transesophageal echocardiography. We intended to identify predictors among admission clinical features, laboratory paramters and culture reports that can help risk stratify patients early in the course of treatment.
Investigators
Sandeep Mohanan
Senior Resident (DM) Cardiology
Government Medical College, Kozhikode
Eligibility Criteria
Inclusion Criteria
- •Fulfillment of modified Duke criteria
Exclusion Criteria
- •No consent
- •inadequate baseline data
Outcomes
Primary Outcomes
Major complications
Time Frame: 30 days
In-hospital mortality
Time Frame: 30 days
Secondary Outcomes
- Short term Mortality(6 months)
- Number of patients who needed urgent cardiac surgery(30 days)
- Number of patients who had embolic events(30 days)