Paramedic Antibiotics for Severe Sepsis: A Phase 2 Study

Ambulance Victoria0 个研究点目标入组 110 人开始时间: 2018年2月7日最近更新: 2021年6月7日

适应症

试验速览

暂无简介。

•Patients are eligible to be enrolled in the PASS study if they present with a history suggestive of infection, are greater than or equal to 18 years of age, are transported to a participating hospital, and who meet the following initial paramedic VSS criteria:
•SBP<100mmHg; and

•Female known to be pregnant
•Suspected or known allergy to any cephalosporin antibiotics (e.g. Ceftriaxone) and confirmed severe allergic reactions to penicillin (e.g. Anaphylaxis or Angio oedema). If unable to confirm severe allergic reactions to penicillin and the patient meets the inclusion criteria (and no other exclusion criteria) enrolment can occur.
•Suspected meningococcal infection (will receive ceftriaxone as standard care)
•Deranged clinical parameters considered likely to be from a non-infective cause (such as dehydration, acute coronary syndrome, trauma, anaphylaxis)
•Already receiving IV antibiotics (Hospital in the home” patients)
•Cystic Fibrosis
•Transplant recipient of solid organs
•Cancer patients receiving active treatment
•Patient has been an in-patient at a health-care facility in the last 7-days

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