Can Biochemical Tests Predict Outcome in Patients With Hip Fracture?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Region Skane
- 入组人数
- 999
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
The objective of the study is to identify biochemical predictors of morbidity and mortality in patients suffering from hip fracture. For this purpose blood samples are collected prehospitally or in the emergency department in patients with a suspected hip fracture. During the hospital stay medical history, anesthesiological management recorded. In addition, american society of anesthesiology physiological score (ASA), revised cardiac risk index (RCRI), and POSSUM score is calculated. Morbidity and mortality is recorded " in house", after 30 days, after 4 months and after 1 year. Biochemical predictors of outcome will be evaluated with logistic regression analysis. Biochemical predictors include pro-brain natriuretic peptide, lactate, pro-calcitonin, adrenomedullin, copeptin, cystatin c. The predictive value of the potential markers will be compared to that of ASA, RCRI and POSSUM.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presenting with out of hospital hip fracture at University Hospital Lund Sweden
- •Informed consent
- •Blood sampling within 3 hrs of first contact with healthcare
排除标准
- •No consent can be obtained
- •Non-operative management
- •Followup through the Swedish National Quality for Hip fracture patients not possible
- •High energy trauma
结局指标
主要结局
Mortality
时间窗: 30 days
次要结局
- Morbidity(30 day)