Preoperative Biochemical Predictors of Outcome in Patients With Hip Fracture
- Conditions
- Hip Fracture
- Registration Number
- NCT01280253
- Lead Sponsor
- Region Skane
- Brief Summary
The objective of the study is to identify biochemical predictors of morbidity and mortality in patients suffering from hip fracture. For this purpose blood samples are collected prehospitally or in the emergency department in patients with a suspected hip fracture. During the hospital stay medical history, anesthesiological management recorded. In addition, american society of anesthesiology physiological score (ASA), revised cardiac risk index (RCRI), and POSSUM score is calculated. Morbidity and mortality is recorded " in house", after 30 days, after 4 months and after 1 year. Biochemical predictors of outcome will be evaluated with logistic regression analysis. Biochemical predictors include pro-brain natriuretic peptide, lactate, pro-calcitonin, adrenomedullin, copeptin, cystatin c. The predictive value of the potential markers will be compared to that of ASA, RCRI and POSSUM.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 999
- Patients presenting with out of hospital hip fracture at University Hospital Lund Sweden
- Informed consent
- Blood sampling within 3 hrs of first contact with healthcare
- No consent can be obtained
- Non-operative management
- Followup through the Swedish National Quality for Hip fracture patients not possible
- High energy trauma
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality 30 days
- Secondary Outcome Measures
Name Time Method Morbidity 30 day Infectious complications Cardiovascular complications Thromboembolic complications Respiratory complications Renal complications Surgical complications
Trial Locations
- Locations (1)
Skane University Hospital, Lund
🇸🇪Lund, Skane, Sweden