The Prediction of Fetal Macrosomia by Measurement of Placenta Volume and Thickness in Pregnant Women With Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- the number of paticipants who will have babies with macrosomias
研究概览
简要总结
Fetal macrosomia defined as birth weight above 90th centile ,macrosomia occurs in 42-62%of pregnancy complicated by type 1 diabetes mellitus ,in 30-56% of pregnancy complicated by type 2 diabetes mellitus .
-The delivery of macrosomic infant has potentially severe consequence for both the newborn and mother .Increased birth weight increase the risk in the fetus of shoulder dystocia and premature brachial plexus injury ,and those infant weighing above 4500g are at increased risk for neonatal morbidity ,including the need for assisted ventilation and meconium aspiration .Maternal complication result from operative delivery and include postpartum hemorrhage ,third or fourth degree laceration and postpartum infection .
详细描述
Estimated fetal body weight is needed especially when head measurement is impossible whenever the fetal head is positioned low in pelvic brim .A convenient method for estimating fetal body weight without head measurement was thus required .
-The human placenta develop with the principal function of providing nutrients and oxygen to the fetus ,adequate fetal growth and subsequent normal birth weight depend on normal placenta .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 43 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •1.Singleton gestational 2.Gestational age over 16-20 weeks 3.Intact membrane 4.Normal umbilical morphology (two arteries and one vein )
排除标准
- •The presence of fetal congenital anomaly .
- •Multifetal pregnancy.
- •Maternal chronic disease (hypertension, renal disease ,and pulmonary disease ,etc.)
- •Patient with a diagnosis such as oligohydramnios ,preeclampsia and intrauterine growth retardation .
- •Patient who used cigarette or alcohol during pregnancy.
结局指标
主要结局
the number of paticipants who will have babies with macrosomias
时间窗: within a week from delivery
To detect number of fetuses who will develop macrosomia
次要结局
未报告次要终点
研究者
Mahmoud Alalfy
Assistant Researcher , National Research centre and Specialist of Obstetrics and Gynecology in Aljazeerah hospital
Aljazeera Hospital