Can muscle growth and strength gains from weight training in young, active, healthy adults be affected by supplementing with palmitoylethanolamide?

Not Applicable

Completed

• Conditions: Skeletal muscle; Musculoskeletal - Normal musculoskeletal and cartilage development and function

• Registration Number: ACTRN12621001726842
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-12-17
• Study Completion: 2023-04-23
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Key inclusion criteria: 1) Male or female 18-35 years of age and have had double COVID-19 vaccination done 2) recreationally active and non-resistance trained 3) have maintained a stable weight for the past 2 months (no more than ±2 kgs of weight change) 4) currently not consuming any other prescribed or non-prescribed analgesics

Exclusion Criteria

Participants will be excluded based on the following: 1) they self-report as having had a musculoskeletal injury in the past 6 months 2) participation in structured resistance training in the past 6 months 3) allergies to any of the contents of the Levagen+ supplement 4)BMI <18.5 or BMI >28 5) currently participating in a weight loss program or special diet (e.g. Low carbohydrate, ketogenic, vegan etc) 6) current smokers 7) acute or terminal illness, functional impairment that would limit inclusion in the trial 8) use of sports supplements or pain medication in the last month 9) current chronic disease including cancer, diabetes, cardiovascular disease, chronic liver disease, and gastrointestinal disorders that affects nutrient absorption 10) cognitive impairment or inability to commit to the study and its requirements.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total body and regional (arms and legs) body composition (amount of muscle and fat) will be assessed using a non-invasive method referred to as dual energy X-ray absorptiometry (DXA)[Familiarisation (week 0), Baseline (week 1) and Post Testing (week 10)];Muscle cross-sectional area in the thigh region will be assessed using peripheral computed tomography (pQCT)[Familiarisation (week 0), Baseline (week 1) and Post Testing (week 10)];Upper body strength will be assessed by 1 repetition maximum bench press.[Familiarisation (week 0), Baseline (week 1) and Post Testing (week 10)]