JPRN-UMIN000013863
Completed
Phase 2
The efficacy of the use of denosumab in the prevention of aromatase inhibitor-induced bone loss in postmenopausal women with hormone receptor-positive breast cancer who are currently on or will iniate an aromatase inhibitor in the adjuvant setting - The efficacy of the use of denosumab in the prevention of AI-induced bone loss in postmenopausal patients
Department of Endocrine and breast cancer, Kyoto Prefectural University of medicine0 sites100 target enrollmentMay 12, 2014
ConditionsBreast Cancer
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Breast Cancer
- Sponsor
- Department of Endocrine and breast cancer, Kyoto Prefectural University of medicine
- Enrollment
- 100
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Diagnosis of clinical or radiological disant metastasis before inclusion 2\) Invasive bilateral breast cancer 3\) Received prior treatment with intravenous bisphosphonates within the past 12 months 4\) Following diseases which may interfere with DXA scan such as severe scoliosis, vertebral diseases 5\) Current active dental problems including infection of the teeth or jawbone. Recent (within 6 weeks) or planned dental or jaw surgery(e.g., extraction, implants) 6\) Other conditions judged as inappropriate for the study by the investigator
Outcomes
Primary Outcomes
Not specified
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