To compare which one,out of dexamethasone and clonidine provides better pain relief when added as an additive in transversus abdominis plane block

Phase 4

Not yet recruiting

• Conditions: Health Condition 1: K00-K95- Diseases of the digestive system

• Registration Number: CTRI/2023/02/049738
• Lead Sponsor: ady Hardinge Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients of either sex, belonging to age group 1-8 years, scheduled for laparotomy

Exclusion Criteria

1. History of any relevant drug allergy or chronic pain

2. Coagulation disorder

3. Infection at the needle insertion site

4. Duration of surgery > 3 hours

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean duration of postoperative analgesia (in hours) in children receiving clonidine or dexamethasone as an adjunct in TAP block for laparotomy <br/ ><br> <br/ ><br>Timepoint: at the end of study <br/ ><br> <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
1. Mean (±SD) requirement of analgesics (μg) in 24 hours postoperatively <br/ ><br>2. Median [ Interquartile range (IQR)] CHEOPS at 30 minute, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively <br/ ><br>3. Proportion of patients developing side effects of the drugs - clonidine or dexamethasone (dry mouth, hypotension, bradycardia) <br/ ><br>4. Median (IQR) University of Michigan Sedation Score (UMSS) at 30 minutes, 3 hours, 6 hours, 12 hours and 24 hours interval. <br/ ><br>5.Median (IQR) parental satisfaction score (Likert scale) at 24 hours postoperatively <br/ ><br>Timepoint: 1.24 hours postoperatively <br/ ><br>2.30 minute, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively <br/ ><br>4. 30 minute, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively <br/ ><br>5.24 hours postoperatively <br/ ><br>