NCT00421018已完成不适用
Optimization of the Anti-Inflammatory Treatment of Asthma Patients Through Exhaled NO Measurements for Increased Asthma-Related Quality of Life in Primary Health Care (NOAK)
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 187
- 试验地点
- 1
- 主要终点
- Mini-AQLQ (Asthma-Related Quality of Life)
研究概览
简要总结
The purpose of this study is to determine whether use of exhaled NO (nitric oxide) to regulate the anti-inflammatory treatment leads to increased asthma-related quality of life in patients with allergic asthma
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-64
- •Clinical diagnosis of Asthma
- •Glucocorticoid treatment > 6 months.
- •Verified Allergy
- •Read and speak Swedish
排除标准
- •Current regular treatment with long-acting beta2-agonist
- •Treatment with Singulair only or in combination with glucocorticoids
- •Taking part in other research study
- •Pregnancy or breast-feeding
- •Unstable Asthma
研究组 & 干预措施
Symptom-guided group
Sham Comparator
Anti-inflammatory treatment is guided conventionally according to symptoms and beta-2-agonist use.
干预措施: Single corticosteroid inhalers and Singulair (Drug)
FeNO-guided group
Active Comparator
Anti-inflammatory treatment is guided according to the level of exhaled nitric oxide
干预措施: Single corticosteroid inhalers and Singulair (Drug)
结局指标
主要结局
Mini-AQLQ (Asthma-Related Quality of Life)
时间窗: 1 year
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
终止
不适用
The Use of Exhaled Nitric Oxide in Conjunction With the Asthma Control Test to Determine Asthma Control in Pediatric PatientsAsthmaNCT00575445Akron Children's Hospital100
已完成
2 期
Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing StrategiesDepressive Disorder, MajorDepressive Disorder, Treatment-ResistantNCT03283670Washington University School of Medicine24
Unknown
4 期
Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric PatientsDental AnxietyPainNCT04083105Children's Hospital Colorado150
Unknown
4 期
Assessment of Utility of Exhaled Nitric Oxide Measurement for Treatment Monitoring in Children With AsthmaAsthmaNCT00500253Medical University of Lodz120
已完成
3 期
Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature BabiesLung DiseaseNCT00551642Mallinckrodt800