The effect of a calcium delivery system on tooth decay in head and neck cancer patients treated by radiotherapy
Completed
- Conditions
- Dental cariesOral Health
- Registration Number
- ISRCTN14942820
- Lead Sponsor
- ational Dental Centre Singapore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
1. Patients aged 21 years or older
2. Ability to understand and provide informed consent prior to starting the study
3. Patient has no advanced periodontal disease
4. Patient has at least eight remaining teeth at start of the study
Exclusion Criteria
1. Patient who has previously undergone head and neck radiotherapy
2. Uncontrolled systemic disease (eg hypertension, diabetes)
3. Patient on palliative care
4. Pregnancy (self declared)
5. Patient with milk allergy (self declared)
6. Patient with hydroxybenzoates (preservative) allergy (self declared)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Caries lesion progression assessed using the International Caries Detection and Assessment System (ICDAS) visual criteria at baseline, 2 weeks and 3 months after completion of radiotherapy
- Secondary Outcome Measures
Name Time Method Fluoride ion concentration in resting saliva measured using a fluoride-specific electrode at baseline, one week before start of radiotherapy, mid-radiotherapy, 2 weeks and 3 months after end of radiotherapy