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Clinical Trials/NCT00712816
NCT00712816
Unknown
Phase 4

Investigating the Use of a Cryopneumatic Therapy Device in Primary Total Knee Arthroplasty Patients

CoolSystems, Inc.11 sites in 2 countries224 target enrollmentJuly 2008

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Osteoarthritis
Sponsor
CoolSystems, Inc.
Enrollment
224
Locations
11
Primary Endpoint
Physical function performance
Last Updated
14 years ago

Overview

Brief Summary

The purpose of the study is to evaluate the effectiveness of a device that delivers cold and intermittent compression as compared to ice and compressive wraps on patients who have undergone knee replacement.

Detailed Description

The use of cryotherapy with compression for orthopedic postoperative recovery has not been fully investigated. A new device has been developed that combines cold and intermittent pneumatic compression in a single system. A well-controlled clinical study evaluating the clinical effectiveness of cryotherapy with compression in an orthopedic postoperative application is the subject of this protocol. Patients diagnosed with osteoarthritis of the knee and scheduled for primary total knee arthroplasty procedure will be invited to participate in this study.

Registry
clinicaltrials.gov
Start Date
July 2008
End Date
May 2012
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • At least 18 but no more than 85 years of age
  • Body Mass Index not greater than 40
  • Diagnosis of osteoarthritis of the knee
  • Medically cleared for total knee replacement surgery
  • Physically and mentally able and willing to participate in and follow the study protocol and schedule
  • Able and willing to have all postoperative physical therapy visits in a physical therapy clinic associated with the research site
  • Signed informed consent document for the study

Exclusion Criteria

  • Rheumatoid arthritis
  • Severe pitting edema in the ipsilateral limb
  • History of thrombophlebitis in lower extremities
  • An active systemic disease such as AIDS, HIV, hepatitis, etc.
  • Is immunologically suppressed or has received or is receiving steroids at any dose daily for more than one month within the last 12 months
  • Is pregnant or planning to become pregnant during the study period
  • Any condition that would contraindicate using the Game Ready
  • Currently enrolled in another clinical trial that could affect outcome of this study
  • Previously enrolled in this study

Outcomes

Primary Outcomes

Physical function performance

Time Frame: 2 weeks postoperative, 6 weeks postoperative, 6 months postoperative

Time to reach defined physical therapy milestones

Time Frame: 2 weeks postoperative, 6 weeks postoperative, 6 months postoperative

Study Sites (11)

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