Soluble fibre for asthma control

Phase 2

Completed

• Conditions: Respiratory - Asthma; Asthma; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12618001362280
• Lead Sponsor: niversity of Newcastle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-08-14
• Study Completion: 2020-05-18
• Last Update Posted: 8 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Males and females aged 18 years and over.
Doctor diagnosis of asthma and confirmed airway hyper-responsiveness
Poorly controlled asthma, defined as ACQ6 >0.75 units

Exclusion Criteria

Recent (past month) respiratory tract infection; respiratory conditions other than asthma; non-adherence to prescribed asthma medications; dietary modifications unsuitable; current diagnosis of diabetes or active gastrointestinal disease; recent antibiotic or laxative use; nutritional, fibre or probiotic supplement use (this includes any vitamin or minerals, sports supplements, meal replacements, probiotics and fibre preparations) within the previous 4 weeks; current smokers; pregnancy or breastfeeding; chronic or excessive alcohol consumption; unexplained weight loss (>5% body weight) in the past 6 months; current use of anti-inflammatory medications (e.g. corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDS)); terminal illness; galactosemia or ragweed allergy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Asthma Control as measured by the Juniper Asthma Control Questionnaire (ACQ7) [Change in asthma control after 2 weeks of each treatment arm compared to placebo.]