Transient Elastography and Variceal Bleeding

Not Applicable

Terminated

• Conditions: Bleeding
• Interventions: Device: Fibroscan

• Registration Number: NCT00635687
• Lead Sponsor: University Hospital, Rouen

Brief Summary

Transient elastography is a new non-invasive rapid and reproducible method, allowing evaluating liver fibrosis by measurement of liver stiffness.

The aim of our study is to evaluate if the liver stiffness can predict the recurrence of upper variceal bleeding in cirrhotic patients hospitalized for variceal rupture.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-03
• Study First Submitted: 2008-03-07
• Study First Submitted QC: 2008-03-13
• Study First Posted: 2008-03-14
• Primary Completion: 2012-03
• Study Completion: 2012-05
• Status Verified: 2013-03
• Last Update Submitted: 2013-03-04
• Last Update Posted: 2013-03-05

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

• Informed consent form signed
• Social security affiliation
• Variceal bleeding with hematemesis or melena within 24 hours of inclusion
• Age > 18 years
• Scheduled to undergo endoscopy within 24 hours of hospital admission

Exclusion Criteria

• Hepatocarcinoma
• Upper Gastro Intestinal bleeding for other causes than variceal bleeding
• Concomitant disease with a life expectancy of less than 45 days
• Rebleeding within 24 hours after first endoscopy
• Technical failure of transient elastography

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Fibroscan	Fibroscan	-

Primary Outcome Measures

Name	Time	Method
Bleeding recurrence rate	J45 post first hemorrage

Trial Locations

Locations (4)

UH Amiens; 🇫🇷 Amiens, France

UH Caen; 🇫🇷 Caen, France

UH Lille; 🇫🇷 Lille, France

Rouen University Hospital; 🇫🇷 Rouen, France