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Proseal Laryngeal Mask Airway or Endotracheal Tube for Emergence From Neuroanesthesia

Not Applicable
Completed
Conditions
Hypertension on Emergence
Registration Number
NCT01718470
Lead Sponsor
Ricard Valero
Brief Summary

Extubation and emergence from anesthesia lead to systemic and cerebral hemodynamic changes that can cause cerebral edema and hemorrhage. The hemodynamic profile on emergence is more favorable if a laryngeal mask airway (LMA) is inserted before neurosurgical patients emerge from anesthesia. We aimed to compare the impact of awakening neurosurgery patients after insertion of a ProSeal LMA to replace the endotracheal tube (ETT).

Detailed Description

At the end of surgery, the anesthesiologist opened a sealed envelope labeled with software-generated randomized numbers to learn the patient's assignment to one of two groups to emerge from anesthesia with the ETT still in place or after it had been replaced by an LMA.

Hemodynamic variables were recorded at 8 moments: baseline, in the operating room one minute before anesthetic induction; 5 minutes after the end of surgery before awakening (ETT group) or before tube replacement (LMA group); and 1, 5, 10, 15, 30 and 60 min after extubation or LMA removal (according to group assignment).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
42
Inclusion Criteria
  • Elective craniotomy
Exclusion Criteria
  • Difficult airway
  • Uncontrolled hypertension before surgery
  • gastroesophageal reflux

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
systolic blood pressure change1 minute before anesthesia induction, 5 minutes before extubation, and minute 1, 5, 10, 15, 30 and 60 after extubation
Secondary Outcome Measures
NameTimeMethod
heart rate change1 minute before anesthesia induction, 5 minutes before extubation, and minutes 1,5,10,15,30 and 60 after extubation

Trial Locations

Locations (1)

Anesthesia department, Hospital Clínic de Barcelona

🇪🇸

Barcelona, Spain

Anesthesia department, Hospital Clínic de Barcelona
🇪🇸Barcelona, Spain

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