Proseal Laryngeal Mask Airway or Endotracheal Tube for Emergence From Neuroanesthesia
- Conditions
- Hypertension on Emergence
- Registration Number
- NCT01718470
- Lead Sponsor
- Ricard Valero
- Brief Summary
Extubation and emergence from anesthesia lead to systemic and cerebral hemodynamic changes that can cause cerebral edema and hemorrhage. The hemodynamic profile on emergence is more favorable if a laryngeal mask airway (LMA) is inserted before neurosurgical patients emerge from anesthesia. We aimed to compare the impact of awakening neurosurgery patients after insertion of a ProSeal LMA to replace the endotracheal tube (ETT).
- Detailed Description
At the end of surgery, the anesthesiologist opened a sealed envelope labeled with software-generated randomized numbers to learn the patient's assignment to one of two groups to emerge from anesthesia with the ETT still in place or after it had been replaced by an LMA.
Hemodynamic variables were recorded at 8 moments: baseline, in the operating room one minute before anesthetic induction; 5 minutes after the end of surgery before awakening (ETT group) or before tube replacement (LMA group); and 1, 5, 10, 15, 30 and 60 min after extubation or LMA removal (according to group assignment).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 42
- Elective craniotomy
- Difficult airway
- Uncontrolled hypertension before surgery
- gastroesophageal reflux
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method systolic blood pressure change 1 minute before anesthesia induction, 5 minutes before extubation, and minute 1, 5, 10, 15, 30 and 60 after extubation
- Secondary Outcome Measures
Name Time Method heart rate change 1 minute before anesthesia induction, 5 minutes before extubation, and minutes 1,5,10,15,30 and 60 after extubation
Trial Locations
- Locations (1)
Anesthesia department, Hospital Clínic de Barcelona
🇪🇸Barcelona, Spain
Anesthesia department, Hospital Clínic de Barcelona🇪🇸Barcelona, Spain