A COMPARATIVE STUDY BETWEEN ISOBARIC LEVOBUPIVACAINE WITH HYPERBARIC BUPIVACAINE IN UROLOGIC SURGERIES: A PROSPECTIVE RANDOMISED CONTROLLED TRIAL
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- To compare the onset, duration of sensory and motor blockade in
研究概览
简要总结
SPINAL ANESTHESIA PLAYS A PIVOTAL ROLE IN MODERN SURGICAL PRACTICE, OFFERING INTRAOPERATIVEANESTHESIA AND POSTOPERATIVE ANALGESIA WHILE MINIMISING SYSTEMIC SIDE EFFECTS. IN UROLOGICAL SURGERIES SPINAL ANESTHESIA IS THE PREFERRED TECHNIQUE DUE TO ITS RAPID ONSET , PREDICTABLE EFFECT AND COST EFFECTIVENESS.A RANDOMISED CONTROLLED DOUBLE BLINDED STUDY IS DONE BETWEEN PATIENTS RECEIVING ISOBARIC LEVOBUPIVACAINE AND HYPERBARIC BUPIVACAINE IN PATIENTS UNDERGOING ELECTIVE UROLOGIC SURGERIES UNDER SPINAL ANESTHESIA. TOTAL SAMPLE SIZE IS 74, WITH 37 PARTICIPANTS IN EACH GROUP.
THE INCLUSION AND EXCLUSION CRITERIA ARE FOLLOWED . INFORMED AND WRITTEN CONSENT FROM PATIENTS WILL BE OBTAINED.PATIENTS WILL BE SHIFTED TO OT ,IV ACCESS WILL BE SECURED, ON THE FOREARM ,IV FLUIDS WILL BE STARTED. MULTIPARA MONITORS WILL BE CONNECTED , UNDER ASEPTIC PRECAUTIONS UNDER SPINAL ANESTHESIA THE DRUG WILL BE ADMINISTERED .HEART RATE , BP, ECG, RR, SPO2, VAS SCALE MODIFIED BROMAGE SCALE ARE MONITORED AND STUDIED.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENTS POSTED FOR ELECTIVE UROLOGIC SURGERIES UNDER SPINAL ANESTHESIA AGE GROUP OF 18-65 YEARS OF AGE BELONGING TO ASA CLASS I AND CLASS II.
排除标准
- •Patient refusal to spinal anesthesia Contraindications to spinal anesthesia like Bleeding disorders and coagulation abnormalities Raised Intracranial pressure Having neurological deficits History of severe migraine and headache.
结局指标
主要结局
To compare the onset, duration of sensory and motor blockade in
时间窗: MODIFIED BROMAGE SCALE HR, SBP, DBP, MAP, ECG, RR, SPO2
patients receiving 0.5% isobaric Levobupivacaine [group L] and patients receiving 0.5%
时间窗: MODIFIED BROMAGE SCALE HR, SBP, DBP, MAP, ECG, RR, SPO2
hyperbaric Bupivacaine [group B] in patients undergoing urologic surgeries.
时间窗: MODIFIED BROMAGE SCALE HR, SBP, DBP, MAP, ECG, RR, SPO2
次要结局
- To compare the intraoperative hemodynamic changes between two groups(To evaluate the adverse effects between the groups)
研究者
SNEHA ANAND
SREE VENKATESHWARA MEDICAL COLLEGE HOSPITAL AND RESEARCH INSTITUTE