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Clinical Trials/NCT04242550
NCT04242550
Completed
Not Applicable

Executive Function Training for Binge Eating Disorder and Comorbid Mood/Anxiety Disorders

University of California, San Diego1 site in 1 country39 target enrollmentJune 23, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Binge-Eating Disorder
Sponsor
University of California, San Diego
Enrollment
39
Locations
1
Primary Endpoint
Feasibility as measured by number of treatment sessions attended
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Binge Eating Disorder (BED) is the most common eating disorder, and currently, the best behavioral treatments only work for 40-60% of adults. BED often co-occurs with mood and anxiety disorders, and both are associated with neurocognitive deficits related to executive function (EF). These EF deficits contribute to worsening BED symptoms and make it difficult for these adults to adhere to treatment recommendations. The proposed study aims to develop an EF training enhanced behavioral treatment for BED and compare its effectiveness to the standard cognitive behavioral therapy for patients with BED and a co-occurring mood or anxiety disorder.

Detailed Description

A randomized controlled trial (RCT) will evaluate an EF training enhanced cognitive behavioral therapy (CBT) for BED (EF-BED+CBT) compared to standard CBT in patients with BED and a comorbid mood/anxiety disorder to assess the feasibility, acceptability, and preliminary efficacy of EF-BED+CBT in reducing binge eating, impairment, and comorbid depression/anxiety symptoms. Adult participants with BED and comorbid mood/anxiety disorder will be randomized to a four month remote treatment of either EF-BED+CBT or CBT alone. Participants will be assessed at baseline, following treatment (month 4) and 2-month follow-up (month 6).

Registry
clinicaltrials.gov
Start Date
June 23, 2020
End Date
November 24, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dawn Eichen

Assistant Adjunct Professor

University of California, San Diego

Eligibility Criteria

Inclusion Criteria

  • Age 18-65
  • Ability to read English at a 6th grade level
  • Clinical or subclinical BED and at least one comorbid mood or anxiety disorder

Exclusion Criteria

  • Known cognitive disability (e.g., brain injury with loss of consciousness \>30 min, intellectual disability)
  • Psychosis
  • Psychiatric condition that could interfere with program participation (e.g., substance abuse, suicide attempt within previous 6 months, active purging, active suicidality)
  • Currently pregnant, lactating or plan to be in the timespan of program follow-up
  • Change in psychotropic medication or other medication that could have impact on weight, binge eating or anxiety/mood symptoms during the previous 3 months
  • Participating in an organized program for overeating

Outcomes

Primary Outcomes

Feasibility as measured by number of treatment sessions attended

Time Frame: Over the course of 4 months of treatment

Attendance at Treatment Sessions

Acceptability

Time Frame: At 4 months

Ratings of usefulness of treatment measured by responses to Likert-type ratings developed by the study team.

Secondary Outcomes

  • Binge Eating(Through study completion, an average of 6 months)
  • Impairment(Through study completion, an average of 6 months)

Study Sites (1)

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