IRCT201405183664N11已完成2 期
Effect of dried hydro alcoholic extract of pomegranate pericarp on oxidattive and inflammation state, Metaloproteinase 1, metabolic markers and clinical sign in women with knee osteoarthritis
Vice chancellor for research of Tabriz University of Medical Sciences0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 38 years 至 60 years（—）
- 性别
- Female
入选标准
- •females aged 38-60 years-old?
- •Primary bilateral knee osteoarthritis with mild to moderate severity based on American College of Rheumatology criteria?
- •Body mass index within range of 30-35 kg/m2 ?
- •Exclusion criteria :
- •Severe osteoarthritis( grade IV)?
- •Secondary knee osteoarthritis based on ACR criteria?
- •knee surgery or intra-articular injection?
- •Neuromuscular diseases ?
- •diabetes? cardiovascular disease? metabolic diseases? kidney and hepatic diseases?
- •Alcohol intake?
- •Vitamin and Mineral,W3, W6 and other antioxidant supplement consumption one month before study and throughout the study?
- •History of MI? History of peptic or duodenal ulcers?
- •Allergy to pomegranate?
- •Use of non-steroidal anti-inflammatory drugs(one week before study until the end of study)?
- •3035kg/m2 ?
排除标准
- 未提供
研究者
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