Hemodynamic and Biological Evaluations During Reventilation Collapse in ICU

• Conditions: Consent of Patients; Adult Patients; Arterial Line; Tracheal Intubation in ICU

• Registration Number: NCT01785654
• Lead Sponsor: University Hospital, Clermont-Ferrand

Brief Summary

Prospective, observational clinical multicentric study in ICU; during the period surrounding the orotracheal intubation.

Detailed Description

Main objective: to describe the characteristics of reventilation collapse: collapse rate, duration and treatment implemented

Secondary objectives:

* identify risk factors of reventilation collapse

* compare mortality, hemodynamic, respiratory, infectious and biological data between collapse group and no reventilation collapse group.

Study Timeline

• Status Verified: 2013-02
• Study First Submitted: 2013-02-01
• Study First Submitted QC: 2013-02-05
• Last Update Submitted: 2013-02-05
• Study First Posted: 2013-02-07
• Last Update Posted: 2013-02-07
• Study Start: 2013-03
• Primary Completion: 2014-11
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Arterial line
• Consent of patients
• Adult patients
• Tracheal intubation in ICU

Exclusion Criteria

• tracheal intubation for cardiac arrest
• pregnant woman
• major protected

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reventilation collapse	at day 1 (at least thirty minutes despite 500 or 1000ml of fluid resuscitation)

Secondary Outcome Measures

Name	Time	Method
mortality	at day 28
reventilation collapse	in the last 72 hours
Duration of mechanical ventilation	at day 1

Trial Locations

Locations (1)

CHU Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France