Online Mindfulness-based Tic Reduction: Development and Testing (Phase Two)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Tourette Syndrome
- Sponsor
- Bowdoin College
- Enrollment
- 37
- Locations
- 2
- Primary Endpoint
- Change in Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Tourette Syndrome (TS) and Persistent Tic Disorder (PTD) are chronic and potentially disabling neurobiological conditions. Although a range of pharmacological and psychosocial treatments exists, a significant number of individuals either do not respond to the current treatments or find them unacceptable. Thus, it is essential that researchers continue to develop and test novel treatment approaches.
In this randomized controlled trial the investigators will compare two different online group-based interventions for tics: a mindfulness-based program (Mindfulness-based Intervention for Tics (MBIT), and a psychoeducational and supportive therapy program (Tic Information and Coping Strategies (TICS)). The purpose of this study is to determine which intervention is more helpful for adults with a tic disorder.
Investigators
Hannah Reese
Assistant Professor
Bowdoin College
Eligibility Criteria
Inclusion Criteria
- •be 18 years of age or older,
- •possess a primary diagnosis of Tourette Syndrome or Persistent Tic Disorder,
- •be fluent in English
- •reside in the United States,
- •either not be taking any tic suppressant medication or other psychotropic medication or be at a stable dose for 8 weeks prior to the baseline assessment and throughout the study
Exclusion Criteria
- •be receiving concurrent psychotherapy for the duration of the study
- •have prior extensive experience with mindfulness and/or meditation and
- •have another medical or psychological condition that would prevent the individual from fully engaging in the study or require a higher level of care (e.g., suicidality).
Outcomes
Primary Outcomes
Change in Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score
Time Frame: Screening, Week 0, Week 9, Week 13, Week 35
Clinician-rated measure of tic severity
Secondary Outcomes
- Clinical Global Impressions Scale(Weeks 0, 9, 13, 35)
- Yale-Brown Obsessive Compulsive Scale(Weeks 0, 9, 13, 35)
- Attention-Deficit Hyperactivity Rating Scale(Weeks 0, 9, 13, 35)
- Depression Anxiety Stress Scale(Weeks 0, 9, 13, 35)
- Tic Rating Form(Weeks 1-8)
- Problem Rating Form(Weeks 1-8)
- Credibility and Expectancy Questionnaire(Week 3)
- Adult Tic Questionnaire(Weeks 0, 9, 13, 35)
- Premonitory Urge to Tic Scale(Weeks 0, 9, 13, 35)
- Patient Health Questionnaire-9(Weeks 0, 9, 13, 35)
- Patient Satisfaction Questionnaire(Week 9)
- Self Compassion Scale(Weeks 0, 9, 13, 35)
- Brief Irritability Test(Weeks 0, 9, 13, 35)
- Work and Social Adjustment Survey(Weeks 0, 9, 13, 35)
- Five Facet Mindfulness Questionnaire(Weeks 0, 4, 8, 9, 13, 35)
- Affective Reactivity Index(Weeks 0, 9, 13, 35)