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Safety and efficacy of low dose MgSo4 regimen for eclampsia treatment

Phase 4
Completed
Registration Number
CTRI/2009/091/000339
Lead Sponsor
Dept of science and technology .chandigarh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

Patients with antepartum eclampsia

Exclusion Criteria

?Comatosed patient
?Pulmonary oedema
?Oliguria /renal failure
?Patient who have received MgSO4, phenytoin, diazepam before coming to hospital.
?Intra-cranial bleeding

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Outcome measures: <br> Maternal ? Recurrence of fits, signs of magnesium toxicity(like loss of knee jerk,respiratory depression) , oliguria any other maternal complications like coagulation failure ,renal failure , pulmpnary oedema will be recorded. Other parameter like need for extra dose for Mgso4, need for diazepam or need for switch over to phenytoin will also be recorded. Details of labour and delivery will be recorded.<br><br>Neonatal: Neonatal outcome like still born ,live born, Aphgar score, hypotonia, respiratory depression , requirement for calcium gluconate ,need for NICU care, jaundice and any other morbidity and mortality will be recorded. <br><br>Timepoint: Till the time of treatment and post partum period
Secondary Outcome Measures
NameTimeMethod
nilTimepoint: nil
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